Clinical Pharmacology
Mostrando 1-12 de 106 artigos, teses e dissertações.
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1. Quais as causas e tratamento para disfagia esofágica?
São várias as causas de disfagia, mas as mais relevantes estão associadas a problemas do esofago e quanto ao manejo, sempre tentar identificar e tratar causa(s) subjacente(s).
A disfagia esofágica pode ser mecânica, (devido ao estreitamento anatômico do lúmen esofágico) ou funcional, (devido a função motora desordenada no esôfago). As med
Núcleo de Telessaúde Espírito Santo. Publicado em: 12/06/2023
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2. Kalanchoe laciniata and Bryophyllum pinnatum: an updated review about ethnopharmacology, phytochemistry, pharmacology and toxicology
Abstract The species Kalanchoe laciniata (L.) DC. and Bryophyllum pinnatum (Lam) Pers. are native from Brazil and Madagascar, respectively. Both belonging to the Crassulaceae family and being widely used by population as a natural anti-inflammatory agent. These species have similar leaf morphology and for this reason, they are known by the same popular name
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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3. A valepotriate-enriched fraction from Valeriana glechomifolia Meyer inhibits leukocytes migration and nociception in formalin test in rodents
Abstract Previous pre-clinical studies demonstrated that a valepotriates enriched fraction from Valeriana glechomifolia F.G. Mey., Caprifoliaceae, was effective against lipopolysaccharide from Escherichia coli (LPS)-induced sickness behavior as well as significantly decreased the cortical expression of pro inflammatory cytokines interleukin-1β and tumor nec
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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4. Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants
Abstract Current challenges to antiretroviral therapy have opened new vistas in the search for novel drugs from natural products. This review focusses on plants as sources of inhibitors for human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Based on a systematic search of the literature, anti-HIV-1 reverse transcriptase activity was recorded
Rev. bras. farmacogn.. Publicado em: 17/10/2019
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5. Analysis of the asynchronous dental teleconsulting of Telehealth Brazil Networks in Minas Gerais
Abstract: This cross-sectional study aimed to evaluate the asynchronous dental teleconsulting of Telehealth Brazil Networks Program in Minas Gerais. Data were collected from secondary databases of the Clinical Hospital of the Universidade Federal de Minas Gerais (CH/UFMG) and Medical School of UFMG (MS/UFMG), from July 2015 to July 2017. The variables analyz
Braz. oral res.. Publicado em: 17/12/2018
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6. The importance of animal studies in Exercise Science
Abstract The validity and relevance of research with animals for the development of knowledge in Exercise Science have for long been discussed. Given the complexity of the biological systems, the use of animal models offers a significant contribution to uncover new findings about acute and chronic effects of exercise, particularly when these studies in human
Motriz: rev. educ. fis.. Publicado em: 02/05/2017
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7. Natural Compounds from Mexican Medicinal Plants as Potential Drug Leads for Anti-Tuberculosis Drugs
ABSTRACT In Mexican Traditional Medicine 187 plant species are used in the treatment of respiratory conditions that may be associated with tuberculosis. In this contribution, we review the ethnobotany, chemistry and pharmacology of 63 species whose extracts have been assayed for antimycobacterial activity in vitro. Among these, the most potent is Aristolochi
An. Acad. Bras. Ciênc.. Publicado em: 09/02/2017
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8. Non-clinical studies in the process of new drug development - Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies
The process of drug development involves non-clinical and clinical studies. Non-clinical studies are conducted using different protocols including animal studies, which mostly follow the Good Laboratory Practice (GLP) regulations. During the early pre-clinical development process, also known as Go/No-Go decision, a drug candidate needs to pass through severa
Braz J Med Biol Res. Publicado em: 12/12/2016
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9. Review on research of the phytochemistry and pharmacological activities of Celosia argentea
ABSTRACT Celosia argentea L., Amaranthaceae, is widely used as traditional medicine with a long history in China. It is a unique source of Semen Celosiae whose contributions include purging the hepatic pathogenic fire, improving eyesight, and treating other eye diseases. Over 79 compounds from this plant were isolated and identified, mainly including saponin
Rev. bras. farmacogn.. Publicado em: 2016-12
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10. Translational microsurgery. A new platform for transplantation research
ABSTRACT PURPOSE: Clinical microsurgery has been introduced in many fields, while experimental microsurgery has the cross-disciplinary features of the sciences and techniques for growth of medicine, pharmacology, veterinary, engineering etc. Training protocol, proposing a new name as Translational Microsurgery, was introduced. METHODS: Reconstructive ski
Acta Cir. Bras.. Publicado em: 2016-03
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11. Carthami flos: a review of its ethnopharmacology, pharmacology and clinical applications
ABSTRACTCarthami flos, the dried floret of Carthamus tinctorius L., Asteraceae (safflower), has been widely used in traditional Chinese medicine to treat a broad range of ailments, such as coronary heart disease, angina pectoris, gynecologic disease, stroke, and hypertension. However, although several studies on Carthami flos have been done consecutively, th
Rev. bras. farmacogn.. Publicado em: 2015-10
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12. Clinical Pharmacology of Caffeine Citrate in Preterm Infants
RESUMO OBJETIVO: A apneia de prematuridade é definida como a interrupção respiratória de 15 a 20 segundos; é o distúrbio respiratório mais importante em prematuros. A apnéia é normalmente tratada com citrato de cafeína. Os objetivos deste artigo são rever: (1) os mecanismos de ação, (2) os efeitos, (3) o metabolismo, (4) a farmacocinética, e
MedicalExpress (São Paulo, online). Publicado em: 2014-10