Clinical Activity
Mostrando 1-12 de 4492 artigos, teses e dissertações.
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1. Quais tratamentos não farmacológicos são recomendados para fibromialgia?
Segundo o Protocolo Clínico e diretrizes terapêuticas publicado em 2014 a maioria dos pacientes beneficia-se da prática regular de atividade física
. Outras terapias não medicamentosas também são eficazes, dentre elas destaca-se a terapia cognitiva comportamental, terapia com calor local e a fisioterapia que podem ser utilizadas em pacientes
Núcleo de Telessaúde Santa Catarina. Publicado em: 12/06/2023
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2. Quais as etapas para tratamento da artrite reumatoide?
Para o tratamento da artrite reumatoide são utilizados classe de medicamentos denominados “
medicamentos modificadores do curso da doença (MMCD): sintéticos
(MMCDs), biológicos (MMCDbio) e
. alvo específico sintéticos
(MMCDsae). A meta terapêutica é a remissão ou baixa atividade da doença. O tratamento inicial, pri
Núcleo de Telessaúde Santa Catarina. Publicado em: 12/06/2023
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3. First-line biologic therapy with tumor necrosis factor inhibitors for psoriatic arthritis: a prospective observational study
ABSTRACT BACKGROUND: Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects multiple joints. It is associated with psoriasis and treated with synthetic and biologic drugs. OBJECTIVE: The objective of this study was to assess the outcomes of patients who received biologic therapy with tumor necrosis factor (TNF) inhibitors in terms of effe
Sao Paulo Medical Journal. Publicado em: 2022
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4. Newborns at high risk for brain injury: the role of the amplitude-integrated electroencephalography
Abstract Objective: Amplitude-integrated electroencephalography (aEEG) is a simplified bedside neurophysiology tool that has been implemented in the neonatal intensive care unit and studied in an extensive range of clinical applications in the past decade. This critical review aimed to evaluate a variety of clinical applications of aEEG monitoring in diagno
Jornal de Pediatria. Publicado em: 2022
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5. Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms
Objective: To characterize rest-activity rhythm in chronic migraine (CM) and to investigate the relationship between this rhythm and depressive and anxiety symptoms in patients with CM. Methods: This was a study of adults aged 20 to 40 years. The rest-activity rhythm of patients with CM (n=23) and non-headache controls (NH, n=23) was assessed by actigraphy
Brazilian Journal of Psychiatry. Publicado em: 2022
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6. Clinical Significance of HSCARG for Atherosclerotic Coronary Heart Disease and Reduced ROS-Oxidative Stress in in Vivo and in Vitro Models via p47phox by NF-κB Activity
ABSTRACT Introduction: Coronary heart disease (CHD) is a dynamic process in which there are interactions between endothelial dysfunction, oxidative stress, and inflammatory responses. The aim of the present study was to investigate the function and mechanism of HSCARG in the treatment of CHD. Methods: Male apolipoprotein E/low-density lipoprotein receptor-
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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7. Application of telesimulation in a medical undergraduate course during the SARS-CoV-2 pandemic: a quantitative and retrospective study
ABSTRACT BACKGROUND: Because of the social isolation and distancing measures that were imposed to stop the spread of coronavirus disease 19 (COVID-19), new ways of teaching were implemented. OBJECTIVES: To describe the implementation of telesimulation and seek to assess students’ perceptions regarding telesimulation. DESIGN AND SETTING: Retrospective qu
Sao Paulo Medical Journal. Publicado em: 2022
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8. Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
Abstract Introduction Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to alterations in its transcriptional activity, acting as a mo
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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9. Does mismatch negativity have utility for NMDA receptor drug development in depression?
Rapid antidepressant effects associated with ketamine have shifted the landscape for the development of therapeutics to treat major depressive disorder (MDD) from a monoaminergic to glutamatergic model. Treatment with ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, may be effective, but has many non-glutamatergic targets, and clinical and logis
Brazilian Journal of Psychiatry. Publicado em: 2022
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10. School Health Education Program “Happy Life, Healthy Heart”: A Randomized Clinical Trial
Abstract Background: School interventions based on playful activities have been shown to be good strategies for increasing children's knowledge about health, which may impact healthy habits. Objective: To evaluate whether the school health education program entitled “Happy Life, Healthy Heart” increases health knowledge and causes a change in teachers�
International Journal of Cardiovascular Sciences. Publicado em: 2022
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11. Does physical activity moderate the association between device-measured sedentary time patterns and depressive symptoms in adults?
Objectives: To investigate the association between sedentary time (ST) patterns and depressive symptoms, and whether moderate-to-vigorous physical activity (MVPA) can moderate this association. Methods: This cross-sectional study included a representative sample of 243 adults (mean age 41.8±16.7 years, 56.4% women) from a city in Southeast Brazil. Depressi
Brazilian Journal of Psychiatry. Publicado em: 2022
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12. Endothelial Progenitor Cells and NADPH Oxidase Enzyme Activity in the Development of an Aortic Aneurysm
Abstract Introduction: Endothelial progenitor cells (EPCs) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme activity may affect the vessel wall and have a role in development of aortic aneurysms. EPCs originate from hematopoietic stem cells and can be enumerated from peripheral blood samples by flow cytometry. In this study, we aimed t
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022