Clavulanic Acid
Mostrando 13-24 de 479 artigos, teses e dissertações.
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13. First characterization of a Providencia stuartii clinical isolate from a Tunisian intensive care unit coproducing VEB-1-a, OXA-2, qnrA6 and aac(6')-Ib-cr determinants
A clinical Providencia stuartii isolate SM662 was recovered from a patient hospitalized in the intensive care unit at the Military hospital, Tunisia. This isolate was resistant to penicillins, cephalosporins, aminoglycosides and fluoroquinolones. A marked in vitro synergy between ceftazidime or cefotaxime and amoxicillin-clavulanic acid on Mueller-Hinton aga
Braz J Infect Dis. Publicado em: 2014-04
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14. Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064
Clavulanic acid (CA) is a powerful inhibitor of the beta-lactamases, enzymes produced by bacteria resistants to penicillin and cefalosporin. This molecule is produced industrially by strains of Streptomyces clavuligerus in complex media which carbon and nitrogen resources are supplied by inexpensive compounds still providing high productivity. The genetic pr
Braz. J. Microbiol.. Publicado em: 24/01/2014
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15. Otimização da etapa de extração do ácido clavulânico presente no caldo de fermentação utilizando misturas de solventes
The purpose of this work was to study four different solvent mixtures intended to increase the yield of the extraction stage of clavulanic acid (CA), which is one of the steps in the purification process. Four central composite rotatable designs (CCRD) were utilized to optimize the solvent mixtures. The variables selected for the factorial design were solven
Quím. Nova. Publicado em: 2014
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16. Prevalence and antibiotic susceptibility of Bacteroides fragilis group isolated from stool samples in North Lebanon
Fifty one strains of the Bacteroides fragilis group were isolated from 45 fecal samples. Classical phenotypic identification showed that 16 isolates were B. thetaiotaomicron, 12 B. uniformis, 9 B. eggerthii,7 B. vulgatus,3 B. caccae,2 Parabacteroides distasonis with 1 identified B. ovatus and 1 B. fragilis. The 51 strains were tested for susceptibility again
Braz. J. Microbiol.. Publicado em: 2013-09
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17. Optimization of the precipitation of clavulanic acid from fermented broth using t-octylamine as intermediate
This work describes the use of clavulanic acid (CA) precipitation as the final step in the process of purification of CA from fermentation broth as an alternative to conventional methods employed traditionally. The purpose of this study was to use a stable intermediate (t-octylamine) between the conversion of CA to its salt form (potassium clavulanate), ther
Braz. J. Chem. Eng.. Publicado em: 2013-06
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18. Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus under different fed-batch conditions
The effect of carbon source and feeding conditions on the production of clavulanic acid (CA) and cephamycin C (CephC) by Streptomyces clavuligerus was investigated. In fed-batch experiments performed with glycerol feeding, production of CA exceeded that of CephC, and reached 1022 mg.L-1. Highest CephC production (566.5 mg.L-1) was obtained in fed-batch culti
Braz. J. Chem. Eng.. Publicado em: 2013-06
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19. Zoonotic potential of multidrug-resistant extraintestinal pathogenic Escherichia coli obtained from healthy poultry carcasses in Salvador, Brazil
The zoonotic potential to cause human and/or animal infections among multidrug-resistant extraintestinal pathogenic Escherichia coli from avian origin was investigated. Twenty-seven extraintestinal pathogenic E. coli isolates containing the increased survival gene (iss) were obtained from the livers of healthy and diseased poultry carcasses at two slaughterh
Braz J Infect Dis. Publicado em: 2013-02
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20. Production and characterization of Streptomyces clavuligerus enzymes related to the biosynthesis of clavulanic acid / Produção e caracterização de enzimas de Streptomyces clavuligerus relacionadas com a síntese do ácido clavulânico
Ácido clavulânico (AC) é um potente inibidor de β-lactamases, produzido por Streptomyces clavuligerus, usado clinicamente em combinação com antibióticos β-lactâmicos para tratar infecções bacterianas resistentes. Apesar da produção industrial de AC já ser bem estabelecida muitos aspectos importantes relacionados com sua biossíntese per
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/12/2012
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21. Attenuated total reflectance with Fourier transform infrared spectroscopy (ATR/FTIR) and different PLS Algorithms for simultaneous determination of clavulanic acid and amoxicillin in powder pharmaceutical formulation
Um método para determinação simultânea de ácido clavulânico (CA) e amoxicilina (AMO) foi desenvolvido utilizando a técnica de espectroscopia no infravermelho médio com transformada de Fourier acoplada ao acessório de reflexão total atenuada (ATR/FTIR). Utilizaram-se 27 e 8 amostras para os conjuntos de calibração e previsão, respectivamente. Os
Journal of the Brazilian Chemical Society. Publicado em: 2011-10
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22. Optimization of clavulanic acid production by Streptomyces daufpe 3060 by response surface methodology
Clavulanic acid is a β-lactam antibiotic which has a potent β-lactamase inhibiting activity. In order to optimize its production by the new isolate Streptomyces DAUFPE 3060, the influence of two independent variables, temperature and soybean flour concentration, on clavulanic acid and biomass concentrations was investigated in 250 mL-Erlenmeyers according
Brazilian Journal of Microbiology. Publicado em: 2011-06
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23. Antimicrobial resistance and prevalence of resistance genes in intestinal Bacteroidales strains
OBJECTIVE: This study examined the antimicrobial resistance profile and the prevalence of resistance genes in Bacteroides spp. and Parabacteroides distasonis strains isolated from children's intestinal microbiota. METHODS: The susceptibility of these bacteria to 10 antimicrobials was determined using an agar dilution method. β-lactamase activity was assesse
Clinics. Publicado em: 2011
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24. Antimicrobial resistance of aerobes and facultative anaerobes isolated from the oral cavity
OBJECTIVES: This study evaluated the resistance to antimicrobials of aerobes and facultative anaerobes isolated from patients wearing complete dentures, patients with gingivitis and periodontitis, and periodontally health subjects. MATERIAL AND METHODS: Three hundred and four isolates were tested. The minimal inhibitory concentrations of the drugs were evalu
Journal of Applied Oral Science. Publicado em: 2010-12