Ciclooxygenases
Mostrando 1-2 de 2 artigos, teses e dissertações.
-
1. Characterization of the inflammatory reaction induced by Bothrops insularis snake venom: leukocyte influx, release of inflammatory mediators and mechanisms involved in this effects / Caracterização da reação inflamatória induzida pelo veneno da serpente Bothrops insularis: Influxo leucocitário, liberação de mediadores inflamatórios e mecanismos envolvidos nesses efeitos
In this study the effects of Bothrops insularis venom (BiV) on the leukocyte influx, on the circulating leukocyte numbers and release of mediators, such as PGD2, PGE2, TXA2, LTB4, MCP-1 and KC into the local of its injection. Moreover, the role of eicosanoids in the BiV- induced leukocyte influx was assessed by selected pharmacological treatments. PMN were a
Publicado em: 2010
-
2. Study of the toxicity induced by the anti-inflammatory sulindac and its metabolites, sulindac sulfone and sulindac sulfide / Estudo da toxicidade induzida pelo antiinflamatório sulindaco e seus metabólitos sulfona e sulfeto
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) known to inhibit non-selectively ciclooxygenases (COX) 1 and 2. Sulindac is therapeutically used as anti-inflammatory and analgesic in the symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, and ankylosing spondylits. In addition to this property, a role in the prevention/
Publicado em: 2006