Chondroitin Sulphate
Mostrando 1-12 de 66 artigos, teses e dissertações.
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1. A prospective randomized controlled multicentre trial comparing intravesical DMSO and chondroïtin sulphate 2% for painful bladder syndrome/interstitial cystitis
ABSTRACT Objective To compare effectiveness of intravesical chondroïtin sulphate (CS) 2% and dimethyl sulphoxide (DMSO) 50% in patients with painful bladder syndrome/interstitial cystitis (PBS/IC). Materials and methods Patients were randomized to receive either 6 weekly instillations of CS 2% or 50% DMSO. Primary endpoint was difference in proportion o
Int. braz j urol.. Publicado em: 2017-02
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2. Construction of a vector for controlled expression of chondroitinase AC for mesenchymal stem cells / Construção de um vetor para expressão controlada de condroitinase AC por células tronco mesenquimais/
Adult mammal axons fail to regenerate when damaged, generating a fundamental problem, inhibiting the recovery of injured central nervous system (CNS). The lack of full regenerative capacity of the injured CNS is due to a glial scar formation on the injury site. The glial scar is formed by astrocytes, oligodendrocyte precursor cells, and microglia, cells that
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2011
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3. Pregnancy malaria: cryptic disease, apparent solution
Malaria during pregnancy can be severe in non-immune women, but in areas of stable transmission, where women are semi-immune and often asymptomatic during infection, malaria is an insidious cause of disease and death for mothers and their offspring. Sequelae, such as severe anaemia and hypertension in the mother and low birth weight and infant mortality in t
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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4. Obtention of human pancreatic islets for transplantation through an increase in cell mass and an immunoisolation with biocompatible microcapsules / Ilhotas pancreáticas humanas viáveis para o transplante através do aumento da massa de células e do imunoisolamento com microcápsulas biocompatíveis
Islet transplantation has been proposed as a promising therapeutic strategy for the cure of type 1 diabetes mellitus (DM), however, its application to all diabetic patients is still not possible due to the limited source of islets or β cells and to the need of an immunosuppressive treatment of the recipient to avoid graft rejection. The use of immunosup
Publicado em: 2009
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5. Determinação espectroscópica multivariada de glucosamina e condroitina em formulações farmacêuticas
The objective of this study was to develop and validate an analytical method for quantification of glucosamine and chondroitin in pharmaceutical formulations. Multivariate calibration combined with infrared spectrophotometry allowed this analysis. 25 mixtures of glucosamine-6-sulphate and chondroitin-6-sulphate were used for calibration. Average errors found
Química Nova. Publicado em: 2008
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6. Terapia laser de baixa potência (904nm) associada ao sulfato de condroitina e quitosana na reparação de defeito osteocondral experimental da cabeça do úmero de cães. Estudo histopatológico / Low laser therapy (904nm) associated with chondroitin sulfate and chitosan on the articular reparation after osteochondral experimental defect on dogs humeral head. Histopathological study
This work was developed in order to evaluate microscoply the influence of gallium arsenate (Ga-As) diodo laser associated with chondroitin sulfate and chitosan on the healing process of the articular surface of the humeral head of dogs following experimental osteochondroplasty. Sixteen adult dogs were randomly allocated into four groups of four animals. All
Publicado em: 2006
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7. Zonal distribution of chondroitin-4-sulphate/dermatan sulphate and chondroitin-6-sulphate in normal and diseased human synovium.
OBJECTIVES--Chondroitin sulphate is the major sulphated glycosaminoglycan present in the extracellular matrix of soft connective tissues and the aim of this study was to investigate the distribution of chondroitin sulphate species in normal and diseased synovium. METHODS--Distribution of chondroitin-4-sulphate/dermatan sulphate (Ch4S/DS) and chondroitin-6-su
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8. Chemical changes of human knee joint menisci in various stages of degeneration.
Human knee joint menisci graded according to degenerative alterations were submitted to chemical analysis. Normal menisci contained 72% water, 0.12% DNA, 22% collagen, and 0.8% total glycosaminoglycans with the following glycosaminoglycan distribution pattern: 40% chondroitin 6-sulphate, 10-20% chondroitin 4-sulphate, 20-30% dermatan sulphate, and 15% kerata
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9. Culture of rat embryos with beta-D-xyloside: evidence of a role for proteoglycans in neurulation.
Day 9 rat embryos were cultured during the period of cranial neurulation in medium containing 1 mm beta-d-xyloside, a substance which inhibits proteoglycan synthesis while stimulating the synthesis of free chains of chondroitin sulphate. The purpose of this investigation was to elucidate the morphogenetic role of chondroitin sulphate, a component of the neur
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10. Dextran sulphate induced arthritis in rabbits.
Persistent effects of a short course of intra-articular dextran sulphate, dextrans, or chondroitin sulphate were examined in rabbit knees. Only dextran sulphate produced gross arthritis, associated with high synovial acid phosphatase and beta-glucuronidase activities. Synovial degradative capacity in synovium-cartilage cocultures was increased 2-fold by dext
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11. Contents and compositions of glycosaminoglycans in different sites of the human hip joint cartilage.
The distribution of glycosaminoglycans (GAGs) in different functional regions (weight-bearing and nonweight-bearing portions) of the human hip joint cartilage was studied. The results obtained were as follows: (1) Weight-bearing cartilage contains larger amounts of GAGs than nonweight-bearing, cartilage. (2) Weight-bearing cartilage contains keratan sulphate
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12. Glycosaminoglycans in the pericellular matrix of chondrons and chondrocytes
This is the first study to quantitate and profile the glycosaminoglycan (GAG) composition of the pericellular matrix (PCM) of chondrons and chondrocytes using the highly sensitive technique; fluorophore-assisted carbohydrate electrophoresis (FACE). Bovine articular chondrocytes and chondrons were isolated enzymatically. High cell yield and viability were obt
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