Chemotherapeutic
Mostrando 1-12 de 622 artigos, teses e dissertações.
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1. Ozone combined with doxorubicin exerts cytotoxic and anticancer effects on Luminal-A subtype human breast cancer cell line
SUMMARY OBJECTIVE: We aimed to examine the potential anticancer effects of ozone applied after chemotherapeutic treatment with different concentrations of doxorubicin in Luminal-A subtype of human breast cancer cell line (MCF-7) and compare the results with effects on L929 fibroblast cell line. METHODS: Both cell lines were incubated with increasing doses
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Mycosis fungoides and Sézary syndrome: focus on the current treatment scenario
Abstract Cutaneous T-cell lymphomas are a heterogeneous group of lymphoproliferative disorders, characterized by infiltration of the skin by mature malignant T cells. Mycosis fungoides is the most common form of cutaneous T-cell lymphoma, accounting for more than 60% of cases. Mycosis fungoides in the early-stage is generally an indolent disease, progressing
An. Bras. Dermatol.. Publicado em: 2021-08
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3. A Symmetrical Dirhenium(I) Complex with 4,4’’-Azobis(2,2’-bipyridine) as a Bridging Ligand: Synthesis, Physicochemical Properties and Applications in Detection of Biologically Relevant Thiols and in Chemotherapy for Bone Cancer
A new dinuclear complex of formula [{Re(CO)3(py)}2(µ-4,4”-azobpy)](PF6)2, with py = pyridine and 4,4”-azobpy = 4,4”-azobis(2,2’-bipyridine), has been synthesized and characterized by spectroscopic and electrochemical techniques. The symmetrical nature of the dimetallic cation has been confirmed by nuclear magnetic resonance (NMR) measurements. When
J. Braz. Chem. Soc.. Publicado em: 2020-11
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4. Drug-induced nephrotoxicity
RESUMO A lesão renal aguda é um diagnóstico muito comum, presente em até 60% dos pacientes críticos, e sua terceira maior causa é a toxicidade de medicamentos. A nefrotoxicidade pode ser definida como qualquer lesão renal causada por medicamentos, direta ou indiretamente, tendo a insuficiência renal aguda, tubulopatias e glomerulopatias como apresent
Rev. Assoc. Med. Bras.. Publicado em: 13/01/2020
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5. Dextrorotatory Chromomycins from the Marine Streptomyces sp. Associated to Palythoa caribaeorum
A Streptomyces sp. (BRA-384) was selected among nine strains of bacteria isolated from the zoanthids Palythoa caribaeorum due to the high cytotoxic activity presented by its EtOAc extract (inhibitory concentration mean (IC50) of 2 ng mL-1) against colon cancer cell line. From the EtOAc extract of BRA-384 three new chemical entities (A6, A7 and A8) and one de
J. Braz. Chem. Soc.. Publicado em: 2020-01
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6. Enhancing Antitumor Efficacy of Cisplatin Low Dose by EDTA in Ehrlich Ascetic Carcinoma Bearing Mice
Abstract In a recent study, the treatment of different human cancer cell lines in vitro with ethylene diamine tetra-acetic acid (EDTA) showed a promising anticancer activity which could be a novel promising approach for cancer treatment. The aim of this study is to address the ability of EDTA to enhance the antitumor efficacy of the low dose of cisplatin (Ci
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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7. Differences between the oral changes presented by patients with solid and hematologic tumors during the chemotherapeutic treatment
Abstract Objective: This study sought to identify the differences between the oral changes presented by patients with solid and hematologic tumors during chemotherapeutic treatment. Methodology: This is an observational, prospective and quantitative study using direct documentation by follow-up of 105 patients from 0 to 18 years using the modified Oral Ass
J. Appl. Oral Sci.. Publicado em: 25/11/2019
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8. Characterization and Cytotoxic Evaluation of Silver and Gold Nanoparticles Produced with Aqueous Extract of Lavandula dentata L. in Relation to K-562 Cell Line
Abstract Metallic nanoparticles have great potential as a chemotherapeutic agent. The aim of this study was to develop and characterize silver and gold nanoparticles using a simple method, as well as evaluating the potential cytotoxic activity in relation to the K-562 cell line. For the synthesis, a solution containing the metallic ions was subjected to mag
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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9. PATIENT SAFETY IN THE ADMINISTRATION OF ANTINEOPLASTIC CHEMOTHERAPY AND OF IMMUNOTHERAPICS FOR ONCOLOGICAL TREATMENT: SCOPING REVIEW
RESUMO Objetivo: identificar e sintetizar as evidências científicas sobre segurança do paciente oncológico na administração de quimioterápicos antineoplásicos e imunoterápicos. Método: scoping review, conforme Joanna Briggs Institute e as recomendações do guia internacional PRISMA-ScR. Realizou-se pesquisa em cinco bases de dados eletrônicas,
Texto contexto - enferm.. Publicado em: 04/11/2019
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10. Evaluation of chemopreventive and chemotherapeutic effect of Artemisia vulgaris extract against diethylnitrosamine induced hepatocellular carcinogenesis in Balb C mice
Resumo O objetivo principal do presente estudo foi investigar as atividades quimiopreventiva e quimioterápica do extrato de Artemisia vulgaris em hepatocarcinogênese induzida por dietilnitrosoamina (DEN) em camundongos Balb C. Dietilnitrosoamina (DEN: 0,9%) foi preparada para induzir hepatocarcinoma em camundongos da linhagem Balb C. O extrato de A. vulgar
Braz. J. Biol.. Publicado em: 04/11/2019
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11. Upregulation of miR-129-5p increases the sensitivity to Taxol through inhibiting HMGB1-mediated cell autophagy in breast cancer MCF-7 cells
Although Taxol has improved the survival of cancer patients as a first-line chemotherapeutic agent, an increasing number of patients develop resistance to Taxol after prolonged treatment. The potential mechanisms of cancer cell resistance to Taxol are not completely clear. It has been reported that microRNAs (miRNAs) are involved in regulating the sensitivit
Braz J Med Biol Res. Publicado em: 28/10/2019
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12. The role of Survivin as a biomarker and potential prognostic factor for breast cancer
RESUMO O câncer de mama (CM) é um dos principais problemas de saúde em todo o mundo. Como o câncer mais comum em mulheres no mundo e no Brasil, precedido apenas pelo câncer de pele não melanoma, essa neoplasia corresponde a aproximadamente 28% dos novos casos por ano no país. O CM também afeta homens, embora a incidência corresponda a apenas 1% do t
Rev. Assoc. Med. Bras.. Publicado em: 22/07/2019