Chemokines
Mostrando 37-48 de 702 artigos, teses e dissertações.
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37. Papel das citocinas e quimiocinas na resposta imunológica murina na infecção por Leptospira interrogans sorovar Copenhageni. / The role of cytokines and chemokines in the murine immune response in infection by Leptospira interrogans serovar Copenhageni.
A leptospirose é uma zoonose causada por bactérias do gênero Leptospira. A patogênese da doença em humanos é observada principalmente no pulmão, fígado e rins. Neste trabalho, foi avaliado o papel da resposta imune inata na proteção contra a leptospirose usando camundongos como modelo experimental. Os animais foram infectados com L. interrogans e o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/05/2012
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38. Influência de materiais odontológicos na capacidade de resposta de fibroblastos cultivados de polpa dental humana / Influence of dental materials on the response capability of cultured fibroblasts from human dental pulp
The aim of the present study is to investigate the influence of dental materials (Single Bond, HEMA, Vitrebond, Ketac Molar e Dycal) in the inflammatory response of human dental pulp fibroblasts from permanent teeth in relation to inflammatory mediators expression. and production. Primary cultures were established from third molars pulp tissue. After the fou
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/04/2012
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39. A influência da flora intestinal e da esplenectomia na resistência à insulina induzida por obesidade / Influence of gut microbiota and splenectomy over the obesity-induced insulin resistance
A high-fat diet intake induces obesity and chronic subclinical inflammation, which play important roles in insulin resistance. Increased circulating levels of proinflammatory cytokines, free fatty acids and lipopolysaccharides activate innate immune system, which triggers inflammation and cytokine expression, leading to insulin resistance. Thus, we investiga
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/03/2012
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40. Relationship between Helicobacter pylori detection and an increased risk of infection in childhood
The risk of developing gastric cancer is believed to be related to differences among Helicobacter pylori strains and the inflammatory responses mediated by host genetic factors. H. pylori infection is acquired at an early age and in the absence of appropriate antibiotic therapy, it generally persists for life. Tp53 gene regulates the transcription of several
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 2012
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41. O papel das quimiocinas CCL3, CCL2 e seus receptores na movimentação dentária ortodôntica
Orthodontic tooth movement (OTM) is achieved by the remodeling of periodontal ligament (PDL) and alveolar bone in response to mechanical loading. This process is regulated by pro-inflammatory mediators, such as cytokines and chemokines. CCL2, CCL3 and CCL5 are chemokines involved in osteoclastogenesis and are upregulated in periodontium after mechanical load
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/11/2011
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42. Estudo in vitro da produção de quimiocinas e pró-colágeno I por fibroblastos de gengiva, ligamento periodontal e polpa dental humanos / In vitro study of chemokines and procollagen I by human gingival, periodontal ligament and dental pulp fibroblasts
Fibroblastos são as células mais numerosas encontradas nos tecidos orais como gengiva, ligamento periodontal e polpa dental. Além de exercerem função estrutural, estas células também desempenham papel importante na resposta imune destes tecidos através do reconhecimento de antígenos e produção de mediadores inflamatórios e citocinas. Evidências
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/08/2011
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43. Avaliação funcional dos eosinófilos na anemia falciforme e o efeito do tratamento com hidroxiureia / Altered functional properties of eosinophils in sickle cell anemia and effects of hydroxyurea therapy
Sickle cell anemia is the homozygous state for hemoglobin S. Inflammation plays an important role in the vaso-occlusive process of the disease, where leukocytes, proinflammatory cytokines and adhesion molecules are increased in the peripheral blood of patients with sickle cell anemia. Leukocytosis is associated with morbidity and mortality in these patients.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/05/2011
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44. Duffy Genotype and Clinical Manifestations Severity in Sickle Cell Anemia / Genótipo Duffy e Gravidade das Manifestações Clínicas na Anemia Falciforme
INTRODUCTION: Sickle cell anemia (SCA) presents with large clinical variability and previous studies suggest that genetic polymorphisms may act as complications predictors. The Duffy antigen appears to play an important role in the removal of inflammatory chemokines from the circulation, suggesting that Duffy-Negative individuals have lower clearance of cyto
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/03/2011
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45. Expression of the chemokine receptor CXCR4 on lymphocytes of leprosy patients
Leprosy is caused by Mycobacterium leprae, which induces chronic granulomatous infection of the skin and peripheral nerves. The disease ranges from the tuberculoid to the lepromatous forms, depending on the cellular immune response of the host. Chemokines are thought to be involved in the immunopathogenesis of leprosy, but few studies have investigated the e
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-12
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46. Dengue-2 and yellow fever 17DD viruses infect human dendritic cells, resulting in an induction of activation markers, cytokines and chemokines and secretion of different TNF-α and IFN-α profiles
Flaviviruses cause severe acute febrile and haemorrhagic infections, including dengue and yellow fever and the pathogenesis of these infections is caused by an exacerbated immune response. Dendritic cells (DCs) are targets for dengue virus (DENV) and yellow fever virus (YF) replication and are the first cell population to interact with these viruses during a
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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47. The effect of combined polymorphisms in chemokines and chemokine receptors on the clinical course of HIV-1 infection in a Brazilian population
Polymorphisms in genes that encode chemokines or their receptors can modulate susceptibility to human immunodeficiency virus (HIV) infection and disease progression. The objective of this study was to assess the frequency of polymorphisms CCR5-Δ32, CCR2-64I, CCR5-59029A and SDF1-3'A and their role in the course of HIV infection in a Southern Brazilian popul
Mem. Inst. Oswaldo Cruz. Publicado em: 2011-06
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48. Staphylococcus aureus regulates secretion of interleukin-6 and monocyte chemoattractant protein-1 through activation of nuclear factor kappaB signaling pathway in human osteoblasts
OBJECTIVE: Activation of nuclear factor kappaB by diverse bacteria regulates the secretion of chemokines and cytokines. Staphylococcus aureus (S. aureus)-infected osteoblasts can significantly increase the secretion of interleukin-6 and monocyte chemoattractant protein-1. The aim of this study was to investigate whether S. aureus can activate nuclear factor
Brazilian Journal of Infectious Diseases. Publicado em: 2011-06