Chagas Disease In Animal Model
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Response to different benznidazole doses in animal models of chronic phase Chagas disease: a critical review
Abstract Chagas disease is a protozoan infection that was identified over a century ago. No drugs are available to treat the indeterminate and determinate chronic phases of the disease. Success of a drug design is dependent on correct biological evaluation. Concerning new drug designs for Chagas disease, it is essential to first identify the most effective,
Rev. Soc. Bras. Med. Trop.. Publicado em: 2018-04
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2. The effect of beta-blockade on myocardial remodelling in Chagas' cardiomyopathy
OBJECTIVE: Chagas' disease has spread throughout Latin America because of the high rate of migration among these countries. Approximately 30% of Chagas' patients will develop cardiomyopathy, and 10% of these will develop severe cardiac damage leading to heart failure. Beta-blockade improves symptoms and survival in heart failure patients; however, its effica
Clinics. Publicado em: 2012-09
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3. Dynamics of regulory T cells (TREG) in the murine infection by Trypanosoma cruzi and its eventual involvement in the chronic cardiac pathology. / Dinâmica das células T reguladoras (TREG) na infecção murina pelo Trypanosoma cruzi e o seu eventual envolvimento na patologia cardíaca na fase crônica.
Uma fração considerável de pacientes com doença de Chagas, decorrente da infecção pelo protozoário Trypanosoma cruzi, desenvolve a cardiopatia crônica, que pode levar a morte. A regulação da resposta imune específica contra o parasita é essencial para controlar a atividade efetora excessiva anti-T. cruzi. Na falta dessa regulação, a resposta im
Publicado em: 2009