Cerebral Ischemia
Mostrando 25-36 de 205 artigos, teses e dissertações.
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25. LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats
Inflammation plays a pivotal role in ischemic stroke, when activated microglia release excessive pro-inflammatory mediators. The inhibition of integrin αvβ3 improves outcomes in rat focal cerebral ischemia models. However, the mechanisms by which microglia are neuroprotective remain unclear. This study evaluated whether post-ischemic treatment with another
Braz J Med Biol Res. Publicado em: 01/08/2016
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26. The protective cardiac effects of Β-myrcene after global cerebral ıschemia/reperfusion in C57BL/J6 mouse
ABSTRACT PURPOSE: To investigate the protective effect of β-myrcene (MYR) on oxidative and histological damage in mice heart tissue caused global cerebral ischemia/reperfusion (IR) in C57BL/J6 mice. METHODS: Animals(n=40) were randomly divided into four groups: (1)control, (2)IR, (3)MYR and (4)MYR+IR. The control group was received 0.1% carboxymethyl cell
Acta Cir. Bras.. Publicado em: 2016-07
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27. Effect of hyperbaric oxygenation on mitochondrial function of neuronal cells in the cortex of neonatal rats after hypoxic-ischemic brain damage
The timing and mechanisms of protection by hyperbaric oxygenation (HBO) in hypoxic-ischemic brain damage (HIBD) have only been partially elucidated. We monitored the effect of HBO on the mitochondrial function of neuronal cells in the cerebral cortex of neonatal rats after HIBD. Neonatal Sprague-Dawley rats (total of 360 of both genders) were randomly divide
Braz J Med Biol Res. Publicado em: 26/04/2016
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28. Dacron Graft Intussusception Technique for Treatment of Type A Aortic Dissections: Technical Notes and Preliminary Results
Abstract Introduction: Optimal surgical management for acute type A aortic dissection (AAAD) remains unclear. The in-hospital mortality rate is still high (15%), and the intraoperative bleeding is an independent risk factor for hospital mortality. Objective: The aim of our study was describe a new method for aortic anastomosis in the repair of AAAD and rep
Braz. J. Cardiovasc. Surg.. Publicado em: 2016-04
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29. Physical exercise prevents motor disorders and striatal oxidative imbalance after cerebral ischemia-reperfusion
Stroke is the third most common cause of death worldwide, and most stroke survivors present some functional impairment. We assessed the striatal oxidative balance and motor alterations resulting from stroke in a rat model to investigate the neuroprotective role of physical exercise. Forty male Wistar rats were assigned to 4 groups: a) control, b) ischemia, c
Braz J Med Biol Res. Publicado em: 28/07/2015
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30. Preconditioning with L-alanyl-glutamine upon cerebral edema and hypocampus red neurons counting in rats subjected to brain ischemia /reperfusion injury
PURPOSE:To evaluate the effects of the dipeptide L-alanyl-glutamine (L-Ala-Gln) as a preconditioning agent to potentially promote reduction in the intensity of lesion or induction of resilience in rats subjected to global cerebral ischemia/reperfusion (I/R) injury.METHODS:Thirty-six male Wistar rats weighing 280-300g were randomly assigned to six groups (n=6
Acta Cir. Bras.. Publicado em: 2015-03
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31. The neuroprotective effect of Sulindac after ischemia-reperfusion injury in rats
PURPOSE: To investigate the neuroprotective effects of Sulindac on the hippocampal complex after global cerebral ischemia/reperfusion (I/R) injury in rats.METHODS: Thirty one Sprague-Dawley rats were used, distributed into group I (sham) n:7 were used as control. For group II (n:8), III (n:8) and IV (n:8) rats, cerebral ischemia was performed via the occlusi
Acta Cir. Bras.. Publicado em: 2014-04
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32. Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition
Sublethal ischemic preconditioning (IPC) is a powerful inducer of ischemic brain tolerance. However, its underlying mechanisms are still not well understood. In this study, we chose four different IPC paradigms, namely 5 min (5 min duration), 5×5 min (5 min duration, 2 episodes, 15-min interval), 5×5×5 min (5 min duration, 3 episodes, 15-min intervals), a
Braz J Med Biol Res. Publicado em: 16/07/2013
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33. Learning and survival memory undergoing a permanent bilateral carotid ligation in rats
PURPOSE: To evaluate the effect of cerebral hypoxia-ischemia on memory and learning survival of rats submitted to permanent bilateral carotid ligation (PBCL). METHODS: Twenty-four survivors of PBCL were evaluated after 30 days with regard to memory and learning using a water survival maze. Twenty-three healthy rats were used as control group. The results wer
Acta Cir. Bras.. Publicado em: 2013-02
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34. Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice
OBJECTIVE: Ischemic stroke may result from transient or permanent reductions of regional cerebral blood flow. Polymorphonuclear neutrophils have been described as the earliest inflammatory cells to arrive in ischemic tissue. CXCR1/2 receptors are involved in the recruitment of these cells. However, the contribution of these chemokine receptors during transie
Clinics. Publicado em: 2013
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35. Potencial evocado auditivo de tronco encefálico em gerbils submetidos à isquemia e sepse / Auditory brainstem response in gerbils submitted to ischemia and sepsis
Introdução: O Acidente Vascular Cerebral do tipo isquêmico é um quadro clínico que afeta milhares de pessoas no mundo. Como resultado dessa injúria observamos morte neuronal, e no decorrer natural de recuperação, o indivíduo pode desenvolver a sepse. A sepse é uma resposta inflamatória sistêmica que pode levar o indivíduo a morte. No seu desenvo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/05/2012
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36. Alterações comportamentais e a análise do estresse oxidativo na idade adulta de animais expostos a hipóxia pré-natal
A Hipóxia-Isquêmica (HI) pré-natal é caracterizada por uma redução no aporte de oxigênio e nutrientes para o feto durante o período gestacional, que pode acarretar, a longo prazo, em dificuldade de concentração e aprendizagem, hiperatividade e déficit de memória. Esses prejuízos podem persistir ou se agravar até a idade adulta, levando ainda ao
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/03/2012