Central Composite Experimental Design
Mostrando 1-12 de 84 artigos, teses e dissertações.
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1. PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger
This work reports the use of the Octave, a free computational software, to optimize the experimental design in the synthesis of ethyl oleate from oleic acid and ethanol catalyzed by a native lipase from Aspergillus niger. The central composite factorial design (CCD) was performed with 2 levels and 3 variables (temperature, mass of native A. niger lipase and
Química Nova. Publicado em: 2022
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2. OPTIMIZATION OF BREWING WASTE’S (TRUB) PHENOLIC COMPOUNDS EXTRACTION BY ULTRASOUND ASSISTED USING RESPONSE SURFACE METHODOLOGY
The brewing waste, also known as trub, is an abundant by-product of the brewing industry. Such material presents high levels of phenolic compounds, which promote antioxidant, antimicrobial and antifungal effects, turning the trub economically attractive. In this study, the trub’s phenolic compounds were extracted by ultrasound-assisted extraction technolog
Quím. Nova. Publicado em: 2021-04
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3. Application of quality by design approach in RP-HPLC method development for simultaneous estimation of saxagliptin and dapagliflozin in tablet dosage form
A simple, sensitive, precise, accurate and robust high performance liquid chromatographic method has been developed for simultaneous estimation of saxagliptin (SAXA) and dapagliflozin (DAPA) in pharmaceutical formulation. Design of experiments (DoE) was applied for multivariate optimization of the experimental conditions of RP-HPLC method. Risk assessment wa
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
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4. Optimal condition of cannabis maceration to obtain the high cannabidiol and Δ9-tetrahydrocannabinol content
Abstract: The aim of this work was to optimize a maceration condition of cannabis (Cannabis sativa L.). A circumscribed central composite experimental design was applied in this work. Temperature and time were varied from 40-80 °C and 30-90 min, respectively. The three responses (i.e., extraction yield, cannabidiol content, and Δ9- tetrahydrocannabinol con
An. Acad. Bras. Ciênc.. Publicado em: 14/10/2019
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5. APPLICATION OF RESPONSE SURFACE METHODOLOGY FOR LIPASE CATALYZED SYNTHESIS OF 2-ETHYLHEXYL PALMITATE IN A SOLVENT FREE SYSTEM USING ULTRASOUND
Abstract This study aims at clean production of 2-ethylhexyl palmitate catalyzed by lipase Fermase CALB 10000 in a solvent-free system using ultrasound technology. The central composite design (CCD) of response surface methodology with 4 factors at 3 levels consisting of acid to alcohol molar ratio (1:3-1:7), enzyme loading (3 %-7% (w/w)), ultrasound power (
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
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6. Preparação, caracterização e avaliação catalítica do compósito Fe2O3/grafite em reação foto-Fenton
RESUMO Neste trabalho, compósito Fe2O3/grafite foi preparado e usado como um catalisador em reação foto-Fenton para a descoloração de solução aquosa contendo o corante amaranto sob irradiação de luz visível. Amostras com diferentes teores de Fe2O3 suportados sobre grafite foram preparadas e caracterizadas por difração de raios-X (DRX), adsorção
Matéria (Rio J.). Publicado em: 16/09/2019
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7. Uso da metodologia de superfície de resposta na otimização da extração de compostos fenólicos da casca dos frutos de Hymenaea courbaril L. (Jatobá)
Resumo Os hábitos alimentares e medicinais dos povos da região Amazônica são ricos em frutos considerados exóticos ou subutilizados comercialmente, alguns dos quais geram considerável quantidade de resíduos. As cascas do fruto de Hymenaea courbaril L. (jatobá) foram submetidas a um processo de extração simultânea de compostos fenólicos, otimizado
Braz. J. Food Technol.. Publicado em: 12/09/2019
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8. Comparison of acid and enzymatic hydrolysis of pectin, as inexpensive source to cell growth of Cupriavidus necator
Abstract: The present work investigated what the appropriate methods of hydrolysis of pectin for reducing compounds (RCs) production, employed as a substrate for cell growth of Cupriavidus necator. This microorganism has great importance industrial, because besides potential single cell protein (SCP), is the most studied microorganism for production of polyh
An. Acad. Bras. Ciênc.. Publicado em: 25/04/2019
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9. Use of Experimental Design to Evaluate the Effect of the Incorporation of Quartzite Residues in Ceramic Mass for Porcelain Tile Production
The potential of using quartzite residues in the composition of an industrial ceramic mass for porcelain tile production was investigated through experimental design. Chemical, physical and microstructural analyses were accomplished to understand how the incorporation of quartzite residues affects the material, before and after sintering. Central composite d
Mat. Res.. Publicado em: 29/10/2018
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10. Surface Integrity Analisys in the Hard Turning of Cemented Steel AISI 4317
This work was based on the surface integrity analysis of hardened steel, AISI 4317 case carburized, quenched and tempered with 58 HRC, obtained by a turning operation executed with CBN (cubic boron nitride) tool, varying three basic cutting parameters (cutting speed, feed rate and cutting depth). The surface integrity characterization was conducted analyzing
Mat. Res.. Publicado em: 26/07/2018
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11. Nutritional and antioxidant potential of a desert underutilized legume – tepary bean (Phaseolus acutifolius). Optimization of germination bioprocess
Abstract Tepary bean (Phaseolus acutifolius) is a short life cycle legume, resistant to many diseases and drought, originally from the deserts and semi-arid environment of Northwestern Mexico and the Southwestern US. Its mature seeds are scarce consumed, and their high protein and carbohydrate contents are underutilized. The aim was to identify optimal germ
Food Sci. Technol. Publicado em: 26/07/2018
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12. Continuous Synthesis of a Green Fuel Additive Mixture with Highest Quantities of Solketalacetin and Solketal and Lowest Amount of Diacetin from Biodiesel-Derived Glycerol
This work presents a continuous, easy-to-scale-up system for glycerol conversion to a valuable fuel additive mixture such as solketalacetin ((2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate), solketal and minimum amount of diacetin with no byproducts. A two-stage reaction was conducted to synthesize the mixture. At first, glycerol was reacted with acetic acid
J. Braz. Chem. Soc.. Publicado em: 2018-06