Cellular Junction
Mostrando 1-12 de 197 artigos, teses e dissertações.
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1. Melanoma associated with congenital intermediate common blue nevus of the scalp - Case report
Abstract: Melanomas can arise either de novo (70%) or from pre-existing melanocytic lesions (30%). Of the latter, most cases arise at the dermoepidermal junction from small congenital or acquired non-blue nevi while only a few arise from blue nevi, notably the cellular subtype and less commonly the common (dendritic) type. Melanomas that arise from blue nevi
An. Bras. Dermatol.. Publicado em: 2016-08
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2. Effect of magnesium ion on human osteoblast activity
Magnesium, a promising biodegradable metal, has been reported in several studies to increase bone formation. Although there is some information regarding the concentrations of magnesium ions that affect bone remodeling at a cellular level, little is known about the effect of magnesium ions on cell gap junctions. Therefore, this study aimed to systematically
Braz J Med Biol Res. Publicado em: 04/07/2016
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3. Neuropeptide Y, substance P, and human bone morphogenetic protein 2 stimulate human osteoblast osteogenic activity by enhancing gap junction intercellular communication
Bone homeostasis seems to be controlled by delicate and subtle “cross talk” between the nervous system and “osteo-neuromediators” that control bone remodeling. The purpose of this study was to evaluate the effect of interactions between neuropeptides and human bone morphogenetic protein 2 (hBMP2) on human osteoblasts. We also investigated the effects
Braz J Med Biol Res. Publicado em: 13/02/2015
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4. Expressão e distribuição celular de proteínas associadas às junções intercelulares no pâncreas endócrino durante o desenvolvimento animal e na diabetes tipo 2 / Cellular expression and distribution of intercellular junction proteins in rodent endocrine pancreas during animal development and type 2 diabetes
As junções intercelulares são especializações da membrana plasmática através das quais células dentro de um tecido podem interagir e aderirem-se umas às outras. Nas ilhotas pancreáticas, as diferentes células endócrinas se interconectam por meio das junções de oclusão, comunicante, aderente e desmossomos. Tais contatos intercelulares parecem s
Publicado em: 2010
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5. Modulação da expressão de conexinas na retina: um estudo morfológico, bioquímico e funcional. / Modulation of connexin expression in retina: a study using morphological, biochemical and functional approaches.
Life is a dynamic process in time and space, resulting from an interaction provided by gap junctions (GJs), channels composed of connexins (Cxs) that permits the passage of molecules up to 1kDa and ions. The aim of this study was analyze the modulation of Cxs during development, dark adaptation and after local mechanical trauma in the retina using techniques
Publicado em: 2009
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6. Papel da comunicação intercelular midiada pelas junções comunicantes no mecanismo de secreção de insulina em modelos in vivo de maturação e disfunção do pancreas endocrino / Intercellular communication mediated by gap junction in in vivo models of pancreatic B-cell maturation and dysfunction
O objetivo central dessa tese foi estudar o papel das junções comunicantes (GJs) no processo de maturação da célula B e na patogênese da diabetes tipo 2. Para isso, foram utilizados dois modelos animais. No modelo in vivo de maturação da célula B e do processo secretório de insulina foram empregados ratos em vários estágios do desenvolvimento (fe
Publicado em: 2009
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7. Imunoexpressão das claudinas -1 e -7 em ameloblastomas e germes dentais humanos
Investigamos a expressão imuno-histoquímica das claudinas -1 e -7 em ameloblastomas e germes dentais humanos, avaliando o padrão de distribuição (focal, regional ou difuso), as células que as expressavam (central ou periférica) e a localização dessa expressão nos constituintes celulares considerando membrana, citoplasma e núcleo. Dentre os 29 caso
Publicado em: 2008
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8. Avaliação do papel da conexina 43 na angiogênese, experimentalmente induzida em córnea de camundongos / Evaluation the role of connexin 43 during angiogenesis, experimentally induced in mice córnea
The GAP junctions are intercellular streams responsible for the communication between close cells, which allow small molecules and ions to pass through them maintaining the cellular homeostasis. The GAP junction is formed of six proteins, the connexin. In the endothelial cell, there are the connexin 37, 40 and 43. In this study, we stimulated the angiogenesi
Publicado em: 2005
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9. Neoplasias melanocíticas cutâneas em cães: aspectos clínicos e histopatológicos em 58 casos / Cutaneous melanocytic neoplasms in dogs: aspects clinics and histopathologics in 58 cases
Thirty nine cases (42 lesions) of melanocytoma and nineteen cases (19 lesions) of canine cutaneous melanoma were analyzed clinic and histopathologically. The melanocytomas affected the young animals as well as the old ones, without a sexual predisposition. The most affected dogs were the ones of the Schnauzer and Doberman breed, being followed by those witho
Publicado em: 2005
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10. Análise da expressão diferencial de genes do folículo ovariano de fêmeas pré-púberes e púberes Bos primigenius indicus (Nelore) por meio da Análise Serial de Expressão Gênica (SAGE) / Analysis of differential gene expression of ovarian follicle from prepubertal and pubertal Bos primigenius indicus (Nelore) females by Serial Analysis of Gene Expression (SAGE)
Puberty is the stage where any mammal, male or female, becomes able to produce viable gametes and manifest complete sexual behavior. These are results from the gradative adjustment between the increase in gonadotrophic activity and the ability of gonads in undergoing simultaneously both steroidogenesis and gametogenesis. One of the major factors interferring
Publicado em: 2005
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11. Gap junctions in cells of the immune system: structure, regulation and possible functional roles
Gap junction channels are sites of cytoplasmic communication between contacting cells. In vertebrates, they consist of protein subunits denoted connexins (Cxs) which are encoded by a gene family. According to their Cx composition, gap junction channels show different gating and permeability properties that define which ions and small molecules permeate them.
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04
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12. Gap junctions in isolated rat aorta: evidence for contractile responses that exhibit a differential dependence on intercellular communication
Connexin43 (Cx43) is a major gap junction protein present in the Fischer-344 rat aorta. Previous studies have identified conditions under which selective disruption of intercellular communication with heptanol caused a significant, readily reversible and time-dependent diminution in the magnitude of a1-adrenergic contractions in is
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-04