Cell Aggregation
Mostrando 1-12 de 882 artigos, teses e dissertações.
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1. NANOTOXICOLOGIA DE NANOPARTÍCULAS DE PRATA: TOXICIDADE EM ANIMAIS E HUMANOS
Silver nanoparticles (AgNPs) have important antimicrobial activity. These nanoparticles are present in several commercial products, leading to human and environmental exposure. This review presents a critical view of the toxic effects of Ag NPs on in vitro and in vivo biological models. It is noteworthy that the toxicity of AgNPs is dependent on several para
Quím. Nova. Publicado em: 2019-02
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2. Cytotoxic and inflammatory potential of a phospholipase A2 from Bothrops jararaca snake venom
Abstract Background: Snake venom phospholipases A2 (PLA2s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA2 isolated from Bothrops jararaca venom, named BJ-PLA2-I. Methods and Results: For its purification, three cons
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018
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3. Cell migration inhibition activity of a non-RGD disintegrin from Crotalus durissus collilineatus venom
Abstract Background: In recent decades, snake venom disintegrins have received special attention due to their potential use in anticancer therapy. Disintegrins are small and cysteine-rich proteins present in snake venoms and can interact with specific integrins to inhibit their activities in cell-cell and cell-ECM interactions. These molecules, known to inh
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 29/11/2018
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4. Lithium carbonate and coenzyme Q10 reduce cell death in a cell model of Machado-Joseph disease
Machado-Joseph disease (MJD) or spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by expansion of the polyglutamine domain of the ataxin-3 (ATX3) protein. MJD/SCA3 is the most frequent autosomal dominant ataxia in many countries. The mechanism underlying MJD/SCA3 is thought to be mainly related to protein misfold
Braz J Med Biol Res. Publicado em: 21/11/2016
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5. Assessment of endothelial function by flow-mediated dilation in diabetic patients: Effects of physical exercise
Abstract The endothelium is now recognized as an endocrine organ that acts to maintain vascular homeostasis regulating the vascular tone and structure. The endothelial cells synthetize a variety of mediators among them, the main agent is the nitric oxide (NO), a potent vasodilator. NO exerts its protective role preventing leukocyte adhesion and migration, ex
Motriz: rev. educ. fis.. Publicado em: 2016-03
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6. Chlorophyllin Derivatives as Photosensitizers: Synthesis and Photodynamic Properties
Two new photosensitizers (PSs) derived from copper-chlorophyllin were designed to have excitation wavelengths appropriate for the use in photodynamic therapy (PDT) and to have amphiphilic character with positive charge, which favors binding to cell membranes and walls and the intracellular localization in mitochondria. Herein we describe the synthesis and ch
J. Braz. Chem. Soc.. Publicado em: 2015-12
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7. Dye Degradation Enhanced by Coupling Electrochemical Process and Heterogeneous Photocatalysis
In this study, we evaluated the combination between an electrochemical process, occurring in the dark, and a heterogeneous photocatalytic process for dye degradation, using the azo dye tartrazine as model of oxidizable substrate. TiO2 P25 and an Ag-doped TiO2 were used as photocatalysts in suspensions containing 50 mg L–1 of tartrazine. The best result, 74
J. Braz. Chem. Soc.. Publicado em: 2015-09
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8. Interaction of an opportunistic fungus Purpureocillium lilacinum with human macrophages and dendritic cells
IntroductionPurpureocillium lilacinum is emerging as a causal agent of hyalohyphomycosis that is refractory to antifungal drugs; however, the pathogenic mechanisms underlying P. lilacinum infection are not understood. In this study, we investigated the interaction of P. lilacinum conidia with human macrophages and dendritic cells in vitro.MethodsSpores of a
Rev. Soc. Bras. Med. Trop.. Publicado em: 2014-10
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9. In vitro evaluation of adhesion and aggregation abilities of four potential probiotic strains isolated from guppy (Poecilia reticulata)
The aim of this work was to study the probiotic-related characteristics of four strains of bacteria isolated from the normal flora of the guppy, Poecilia reticulata. In vitro results showed that the strains, namely, MBTU_PB1, MBTU_PB2, MBTU_PB3 and MBTU_PB4 had higher adhesion abilities than the tested indicator strains. However, an association between the c
Braz. arch. biol. technol.. Publicado em: 2013-10
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10. Obtenção e caracterização de ftalocianinas com substituintes quirais com potencial aplicação em terapia fotodinâmica / Synthesis and characterization ofphthalocyanines with chiralsubstituints with potencialfor use in Photodynamic Therapy
The main objective of this project is the synthesis and characterization of new phthalocyanines with chiral substituents to improve their photophysical and photochemical properties for use as photosensitizers in Photodynamic Therapy. Three new phthalocyanines were synthesized and characterized, one with the racemic mixture of 1-(4-bromophenyl)- ethanol, and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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11. Changes in hyphal morphology due to chitosan treatment in some fungal species
In this work, changes in the hyphal morphology due to chitosan treatment in some fungal species were studied. Scanning electron microscope (SEM) observations revealed that chitosans with molar fraction of acetyl groups (F A 0.16 and 0.18) and degree of polymerization (DP 1,089 and 1,242) had a direct effect on the morphology of the chitosan-treated fungi, re
Braz. arch. biol. technol.. Publicado em: 2012-10
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12. Estudos funcionais da proteína reguladora humana Ki-1/57 e seus parceiros de interação / Functional studies of the human regulatory protein Ki-1/57 and its interaction partners
The protein Ki-1/57 was discovered through cross reactivity of the monoclonal antibody Ki-1 in cells of Hodgkin lymphoma. Previously studies demonstrated that Ki-1/57 interacts with RACK-1 protein, undergoes phosphorylation by PKCs and methylation by PRMT1, an arginine methyltransferase that modulates several RNA binding proteins. Studies have shown that Ki-
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/07/2011