Ccr5q32
Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Analysis of the CCR5 gene coding region diversity in five South American populations reveals two new non-synonymous alleles in Amerindians and high CCR5*D32 frequency in Euro-Brazilians
The CC chemokine receptor 5 (CCR5) molecule is an important co-receptor for HIV. The effect of the CCR5*D32 allele in susceptibility to HIV infection and AIDS disease is well known. Other alleles than CCR5*D32 have not been analysed before, neither in Amerindians nor in the majority of the populations all over the world. We investigated the distribution of t
Genetics and Molecular Biology. Publicado em: 16/01/2009
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2. AvaliaÃÃo da mutaÃÃo ccr5A32 do receptor da B â quimiocina como marcador genÃtico-histÃrico na populaÃÃo de Triunfo Pernambuco / AvaliaÃÃo da mutaÃÃo ccr5A32 do receptor da B â quimiocina como marcador genÃtico-histÃrico na populaÃÃo de Triunfo Pernambuco
The CMKBR5 encodes a 7-transmembrane G-protein-coupled chemokine receptor (CCR5) in macrophages and lymphocytes. A 32 base pair deletion in the coding region of the ccr5 gene has been reported in individuals, homozygous for this deletion, who seem to be resistant to HIV-1 infection. This mutation has a single recent origin in Northeastern Europe, where the h
Publicado em: 2008