Cationic Synthetic Polymers
Mostrando 1-6 de 6 artigos, teses e dissertações.
-
1. Cholesterol improves the transfection efficiency of polyallylamine as a non-viral gene delivery vector
ABSTRACT Cationic polymers such as polyallylamine (PAA) having primary amino groups are poor transfection agents and possess a high cytotoxicity index when used without any chemical modification. In this study, PAA was modified with cholesterol in order to improve transfection efficiency and to reduce cytotoxicity. PAA polymers with molecular weights of 15 a
Braz. J. Pharm. Sci.. Publicado em: 26/10/2017
-
2. Dispersion degree and zeta potential of hematite
Abstract The dispersion degree of the mineral particles in the pulp is especially relevant regarding the performance of the cationic reverse flotation of iron ores. The gangue minerals should remain dispersed while hematite particles should be selectively flocculated. The present study addressed determinations of dispersion degree and zeta potential of hemat
Rem: Rev. Esc. Minas. Publicado em: 2016-06
-
3. Post-treatment of effluents from anaerobic reactor treating domestic sewage by flotation/filtration pilot system with cationic synthetic polymers / Emprego de polímeros em unidade piloto de floto-filtração como pós-tratamento de efluentes de reatores anaeróbios de leito expansível tratando esgoto sanitário
This work assessed the performance of domestic sewage treatment pilot unit consisting of anaerobic reactor followed dissolved-air flotation/filtration (DAFF). Associated ferric chloride was used polyelectrolytes. First, was tested in lab-scale dissolved-air flotation (LSDAF), low dosages of cationic synthetic polymer with high molecular weight as aiding of f
Publicado em: 2008
-
4. Algal Flocculation with Synthetic Organic Polyelectrolytes
The feasibility of removing algae from water and wastewater by chemical flocculation techniques was investigated. Mixed cultures of algae were obtained from both continuous- and batch-fed laboratory reactors. Representative cationic, anionic, and nonionic synthetic organic polyelectrolytes were used as flocculants. Under the experimental conditions, chemical
-
5. Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency.
Clinical applications of gene therapy mainly depend on the development of efficient gene transfer vectors. Large DNA molecules can only be transfected into cells by using synthetic vectors such as cationic lipids and polymers. The present investigation was therefore designed to explore the physicochemical properties of cationic lipid-DNA particles, with plas
-
6. Gene delivery by dendrimers operates via a cholesterol dependent pathway
Understanding the cellular uptake and intracellular trafficking of dendrimer–DNA complexes is an important prerequisite for improving the transfection efficiency of non-viral vector-mediated gene delivery. Dendrimers are synthetic polymers used for gene transfer. Although these cationic molecules show promise as versatile DNA carriers, very little is known
Oxford University Press.