Cationic Bilayers
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Peptidomic analysis of the venom of the solitary bee Xylocopa appendiculata circumvolans
Abstract Background: Among the hymenopteran insect venoms, those from social wasps and bees - such as honeybee, hornets and paper wasps - have been well documented. Their venoms are composed of a number of peptides and proteins and used for defending their nests and themselves from predators. In contrast, the venoms of solitary wasps and bees have not been
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 28/09/2017
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2. Caracterização estrutural de agregados formados pelo antifúngico anfotericina B e lipídios catiônicos: uma possível formulação farmacológica / Structural characterization of aggregates formed by the antifungal drug amphotericin B and cationic lipids: a possible pharmacological formulation
Amphotericin B (AB) is a natural antibiotic, produced by Streptomyces nodosus, with a very potent antifungal activity. It is a polyene macrolide molecule, isolated in 1953. Since then, it has been extensively used in the treatment of systemic mycotic infections. Considering AB very low solubility in aqueous medium, it has been largely used as an aqueous disp
Publicado em: 2008
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3. Interações entre DNA de bacteriófagos e partículas biomiméticas catiônicas / Interactions between Bacteriophage DNA and Cationic Biomimetic Particles
A associação entre DNA de cadeia de longa e partículas catiônicas foi caracterizada por determinações de tamanho (espalhamento de luz dinâmico), análise de potencial-zeta, turbidimetria, estabilidade coloidal, microscopia de força atômica (AFM) e determinação de citotoxicidade dos arranjos contra a bactéria E. coli a partir da contagem de unidad
Publicado em: 2008
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4. A mathematical model describing the kinetic of cationic liposome production from dried lipid films adsorbed in a multitubular system
Cationic liposomes are an alternative to DNA non-viral carrier in gene therapy, promoting higher efficiency for transport and delivery into the cells. Liposome production large scale is still a challenge. Among many processes, from dried film adsorbed inside multitubular system promising due its operational simplicity. this field, engineering contributions s
Brazilian Journal of Chemical Engineering. Publicado em: 2007-12
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5. Estudo do Segmento Consenso Adjacente ao Domínio TM2 e parte do Domínio TM2 do Receptor P2X7: Dinâmica Molecular e Atividade de Canal Iônico. / Study of the segment adjacent consensus to domain TM2 and part of domain TM2 of receiver P2X7: molecular dynamics and activity of ionic canal.
The purinergic receptor P2X7 (P2X7R) is a membrane protein which forms channels in the presence of extracellular ATP. Once opened, the channels allow the transport of cations through the cellular membrane, being expressed preferentially in immune cells. Among all purinergic receptors, P2X7R has distinct characteristics from other P2X (P2XR) members. For exam
Publicado em: 2007
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6. "Propriedades estruturais de agregados anfifílicos catiônicos: interação com material genético" / structural properties of cationic amphiphilic aggregates: interaction with genetic material
Though less efficient than viral vectors, cationic lipids have been used as carriers in gene therapy. They offer several advantages over viral vectors, including the low immunogenic and inflammatory responses, the potential transfer of unlimited-size expression units, and the possibility for engineered cell-specific targeting. However, the interaction betwee
Publicado em: 2006
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7. Estudo da orientação molecular em filmes automontados de azopolímeros por meio da técnica de geração de segundo harmônico (SHG) / Molecular orientation in self-assembled azo-polymer thin films studied by second harmonic generation (SHG).
Ultrathin films of polymers containing azochromophores are important for many applications such as optical data storage, formation of surface relief gratings, liquid crystal alignment layers and non-linear optical devices. Among several techniques for fabricating organic thin films, the Layer-By-Layer electrostatic self-assembly (LBL) is very attractive due
Publicado em: 2006
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8. Cationic bilayers over silica: adsorption and colloidal stability at low ionic strength / Bicamadas catiônicas em sílica: adsorção e estabilidade coloidal a baixa força iônica
The study of adsorption of model-membranes on the surface of solid partic1es is an important line of research in rapidly developing research areas such as biosensors design, building up of immunological kits or design ofbiocompatible materiais. In this work, interactions between hidrophilic silica particles and cationic liposomes made up of dioctadecyldimeth
Publicado em: 2003
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9. Interactions between cationic liposomes and drugs or biomolecules
Multiple uses for synthetic cationic liposomes composed of dioctadecyldimethylammonium bromide (DODAB) bilayer vesicles are presented. Drugs or biomolecules can be solubilized or incorporated in the cationic bilayers. The cationic liposomes themselves can act as antimicrobial agents causing death of bacteria and fungi at concentrations that barely affect mam
Anais da Academia Brasileira de Ciências. Publicado em: 2000-03
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10. Multilamellar structures of DNA complexes with cationic liposomes.
Studies of DNA complexes with cationic liposomes are prompted by the search for nonviral DNA carriers for gene therapy. Recent experiments have identified a stable multilamellar phase in which ordered smectic layers of DNA alternate with cationic bilayers. In this paper we identify the forces governing DNA adsorption on cationic lamellae, including a membran
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11. Plasmid DNA size does not affect the physicochemical properties of lipoplexes but modulates gene transfer efficiency.
Clinical applications of gene therapy mainly depend on the development of efficient gene transfer vectors. Large DNA molecules can only be transfected into cells by using synthetic vectors such as cationic lipids and polymers. The present investigation was therefore designed to explore the physicochemical properties of cationic lipid-DNA particles, with plas
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12. Incorporation in lipid bilayers of a large conductance cationic channel from mitochondrial membranes.
Membranes from subcellular fractions of adrenal medulla were incorporated in phospholipid bilayers formed at the tip of microelectrodes. Current fluctuations recorded in the presence of a transmembrane potential revealed the existence of a voltage-dependent channel of large conductance. This channel is characterized by fast kinetics and four conductance leve