Cardiac Hypertrophy
Mostrando 25-36 de 485 artigos, teses e dissertações.
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25. Time-course effects of aerobic exercise training on cardiovascular and renal parameters in 2K1C renovascular hypertensive rats
Exercise training (Ex) has been recommended for its beneficial effects in hypertensive states. The present study evaluated the time-course effects of Ex without workload on mean arterial pressure (MAP), reflex bradycardia, cardiac and renal histology, and oxidative stress in two-kidney, one-clip (2K1C) hypertensive rats. Male Fischer rats (10 weeks old; 150�
Braz J Med Biol Res. Publicado em: 11/08/2015
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26. ECG-based detection of left ventricle hypertrophy
Introduction Left ventricle hypertrophy (LVH) is an important risk factor for cardiovascular morbidity and mortality. It is characterized by a thickening of the walls of the left ventricle. The transthoracic echocardiogram is a very accurate method for LVH detection. However, the electrocardiogram (ECG) offers an alternative method in diagnosing LVH, besid
Res. Biomed. Eng.. Publicado em: 2015-04
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27. Global microRNA profiles and signaling pathways in the development of cardiac hypertrophy
Hypertrophy is a major predictor of progressive heart disease and has an adverse prognosis. MicroRNAs (miRNAs) that accumulate during the course of cardiac hypertrophy may participate in the process. However, the nature of any interaction between a hypertrophy-specific signaling pathway and aberrant expression of miRNAs remains unclear. In this study, Spague
Braz J Med Biol Res. Publicado em: 11/04/2014
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28. The role of oxytocin in cardiovascular regulation
Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP) into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT)-ergic neurons is responsible for ANP release, and it has become clear that activation of neur
Braz J Med Biol Res. Publicado em: 18/03/2014
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29. Aerobic exercise improves the inflammatory profile correlated with cardiac remodeling and function in chronic heart failure rats
OBJECTIVE: The aim of the present study was to evaluate the effect of 8 weeks of aerobic exercise training on cardiac functioning and remodeling and on the plasma levels of inflammatory cytokines in chronic heart failure rats. METHODS: Wistar rats were subjected to myocardial infarction or sham surgery and assigned to 4 groups: chronic heart failure train
Clinics. Publicado em: 2013-06
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30. Utilização farmacológica de um composto inédito derivado de quinazolina como inibidor potencial da quinase de adesão focal (FAK) no processo de hipertrofia cardíaca em camundongo = : Pharmacological use of a novel compound quinazoline derivative as potential inhibitor of the focal adhesion kinase in the process of cardiac hypertrophy in mice / Pharmacological use of a novel compound quinazoline derivative as potential inhibitor of the focal adhesion kinase in the process of cardiac hypertrophy in mice
Nas doenças do coração ocorre hipertrofia e remodelamento do ventrículo esquerdo com impacto negativo na evolução clínica. Esses fatores influenciam independentemente o risco cardiovascular por elevarem a predisposição a infartos do miocárdio, ao desenvolvimento de insuficiência cardíaca e ao aparecimento de arritmias ventriculares graves. Estrut
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/07/2012
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31. Avaliação experimental do metabolismo energético em dois protocolos de sobrecarga sistólica do ventrículo direito / Experimental evaluation of energy metabolism in two right ventricle systolic overload protocols
Objective: Altered energy metabolism has been identified in myocardial hypertrophy. Some processes are considered beneficial, whereas others are linked to heart failure. The purpose of this study was to compare the activity of three different energy metabolism enzymes in two different protocols of right ventricle (RV) systolic overload in young goats. Method
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/03/2012
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32. Fenofibrato (agonista do receptor ativador da proliferação peroxissomal) modula o sistema renina-angiotensina no coração de camundongos alimentados com dieta hiperlipídica / Fenofibrate (peroxisome proliferator-activated receptor alpha agonist) modulates the renin-angiotensin system in the heart of mice fed with a high-fat diet
The aim was to study the action of fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, in cardiac remodeling and protein expressions of RAS components in a model of obesity induced by diet. 3-mo-old C57BL/6 male were fed for 11 weeks with standard chow (SC group, 3.57 kcal/g of chow) or high-fat chow (HF group, 5.40 kcal/g of chow), then
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/03/2012
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33. Análise da hipertrofia cardíaca induzida pela associação de anabolizante a treinamento físico resistido de alta intensidade, em ratos / Analysis of cardiac hypertrophy induced by nandrolone and physical training of high intensity in rats
A associação entre o tratamento com o esteróide anabólico nandrolona e treinamento físico resistido de alta intensidade induziu hipertrofia cardíaca concêntrica, disfunção sistólica e diastólica em ratos. O objetivo deste trabalho foi avaliar se esta hipertrofia seria patológica, por meio da análise da expressão gênica de marcadores de hipertr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
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34. The role of Ca2+/calmodulin-dependent protein kinase II and calcineurin in TNF-α-induced myocardial hypertrophy
We investigated whether Ca2+/calmodulin-dependent kinase II (CaMKII) and calcineurin (CaN) are involved in myocardial hypertrophy induced by tumor necrosis factor α (TNF-α). The cardiomyocytes of neonatal Wistar rats (1-2 days old) were cultured and stimulated by TNF-α (100 μg/L), and Ca2+ signal transduction was blocked by several antagonists, including
Braz J Med Biol Res. Publicado em: 2012-11
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35. Influência do sistema renina angiotensina na modulação do estado redox, no balanço autonômico e na hipertrofia cardíaca induzida pelo hipertireoidismo experimental
Hyperthyroidism is an epidemiologic relevant pathology, which substantially affects the cardiovascular system. The hyperthyroid state may affect basal metabolism, O2 cell consumption, renin-angiotensin system, and increase reactive oxygen species production. Those alterations produce morphological, biochemical, functional and molecular consequences in cardia
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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36. Análise da função ventricular direita em dois protocolos de treinamento com bandagem ajustável do tronco pulmonar / Assessment of right ventricular function in two training protocols with adjustable pulmonary banding
The ideal surgical treatment of transposition of the great arteries is the Jatene operation during the neonatal period. If the neonate remains untreated for several reasons, the left ventricle may become unprepared to sustain systemic circulation. The preparation of the subpulmonary ventricle by pulmonary trunk (PT) banding is an option for the 2-stage Jaten
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/12/2011