Carbapenemase
Mostrando 1-12 de 91 artigos, teses e dissertações.
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1. Antibacterial activity of essential oils encapsulated in chitosan nanoparticles
Abstract In this study, cinnamon (Cinnamomum zeylanicum), thyme (Thymus vulgaris) and Schinus molle essential oils (at 125, 250 and 500 µg/mL) were encapsulated in chitosan nanoparticles by ionotropic gelation. Their antimicrobial activity against Staphylococcus aureus ATCC 25923, Enterococcus sp., Escherichia coli ATCC 25922, Klebsiella pneumoniae (BLEE +)
Food Sci. Technol. Publicado em: 2020-12
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2. Mobile genetic elements associated with carbapenemase genes in South American Enterobacterales
ABSTRACT Introduction: Carbapenem resistance in members of order Enterobacterales is a growing public health problem causing high mortality in developing and industrialized countries. Its emergence and rapid propagation worldwide was due to both intercontinental spread of pandemic strains and horizontal dissemination via mobile genetic elements (MGE) such a
Braz J Infect Dis. Publicado em: 2020-06
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3. Evaluation of in vitro activity of ceftolozane-tazobactam against recent clinical bacterial isolates from Brazil - the EM200 study
ABSTRACT Background: The emergence of antibiotic resistance is increasing and there are few effective antibiotics to treat infections caused by resistant and multidrug resistant bacterial pathogens. This study aimed to evaluate the in vitro activity of ceftolozane-tazobactam against clinical bacterial isolates from Brazil. Methods: A total of 673 Gram-nega
Braz J Infect Dis. Publicado em: 2020-04
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4. Investigation of carbapenemases and aminoglycoside modifying enzymes of Acinetobacter baumannii isolates recovered from patients admitted to intensive care units in a tertiary-care hospital in Brazil
Abstract INTRODUCTION: Acinetobacter baumannii are opportunistic bacteria, highly capable of acquiring antimicrobial resistance through the production of carbapenemases and aminoglycoside modifying enzymes (AMEs). METHODS: Carbapenemase and AME genes were investigated in A. baumannii recovered from inpatients of a Brazilian hospital. RESULTS: The key gen
Rev. Soc. Bras. Med. Trop.. Publicado em: 20/12/2019
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5. Direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry and real-time PCR in a combined protocol for diagnosis of bloodstream infections: a turnaround time approach
ABSTRACT Bloodstream infections (BSIs) are serious infections associated with high rates of morbidity and mortality. Every hour delay in initiation of an effective antibiotic increases mortality due to sepsis by 7%. Turnaround time (TAT) for conventional blood cultures takes 48 h, forcing physicians to streamline therapy by exposing patients to broad-spectru
Braz J Infect Dis. Publicado em: 09/09/2019
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6. High rate of detection of OXA-23-producing Acinetobacter from two general hospitals in Brazil
Abstract INTRODUCTION In recent decades, the prevalence of carbapenem-resistant Acinetobacter isolates has increased, and the production of oxacillinase (OXA)-type carbapenemases is the main mechanism underlying resistance. We evaluated OXA production from 114 Acinetobacter isolates collected between March and December 2013 from different clinical specimen
Rev. Soc. Bras. Med. Trop.. Publicado em: 05/09/2019
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7. Epidemiological profile of healthcare-associated infections caused by Carbapenemase-producing Enterobacteriaceae
RESUMO Objetivo: Levantar o perfil epidemiológico das Infecções relacionadas à Assistência à Saúde causadas por Enterobactérias que carreiam o gene Klebsiella pneumoniae Carbapenemase (blaKPC) no ambiente hospitalar. Método: Estudo descritivo, realizado em um hospital privado de Belo Horizonte, MG, Brasil que incluiu todos os pacientes com infec
Rev. esc. enferm. USP. Publicado em: 04/07/2019
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8. Infection related to Klebsiella pneumoniae producing carbapenemase in renal transplant patients
ABSTRACT Objective: To evaluate the risk factors related to Klebsiella pneumoniae carbapenemase infection after renal transplantation. Methods: This was a retrospective epidemiological (case-control) study, conducted from October 2011 to march 2016. Transplanted patients with infection by this bacteria during hospitalization were selected as cases. The con
Rev. Bras. Enferm.. Publicado em: 27/06/2019
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9. Origanum vulgare L. essential oil inhibits the growth of carbapenem-resistant gram-negative bacteria
Abstract INTRODUCTION: Plant products are sources for drug development against multidrug resistant bacteria. METHODS The antimicrobial activity of Origanum vulgare L. essential oil (OVeo) against carbapenem-resistant strains was assessed by disk-diffusion, microdilution (REMA-Resazurin Microtiter Assay), and time kill assays. RESULTS Carbapenemase prod
Rev. Soc. Bras. Med. Trop.. Publicado em: 27/06/2019
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10. Economic burden of inpatients infected with Klebsiella pneumoniae carbapenemase
RESUMO Objetivo: Estimar os custos médicos diretos da terapia medicamentosa de pacientes com infecção por carbapenemase por Klebsiella pneumoniae carbapenemase (KPC) em contexto hospitalar. Métodos: Estudo de custo de doença realizado com desenho de coorte prospectiva, com adultos hospitalizados infectados por KPC. A coleta de dados foi realizada usan
Einstein (São Paulo). Publicado em: 16/05/2019
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11. Prevalência de carbapenemases em enterobactérias com sensibilidade diminuída aos carbapenêmicos isoladas em um hospital de referência terciária
RESUMO As infecções causadas por enterobactérias com resistência aos carbapenêmicos são um grave problema de saúde pública. Este trabalho tem como objetivo analisar os mecanismos de resistência relacionados com as enterobactérias com sensibilidade diminuída aos carbapenêmicos isoladas no Hospital Júlia Kubitschek (HJK) da Fundação Hospitalar d
J. Bras. Patol. Med. Lab.. Publicado em: 2018-04
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12. Clonal relation and antimicrobial resistance pattern of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Enterobacter spp. isolated from different clinical samples in Tehran, Iran
Abstract INTRODUCTION: Here, we determined the genes encoding antibiotic resistance enzymes and virulence factors and evaluated the genetic relationship between Enterobacter spp. isolated from different clinical samples. METHODS: A total of 57 clinical isolates of Enterobacter spp. were tested for the production of extended-spectrum β-lactamases (ESBLs)
Rev. Soc. Bras. Med. Trop.. Publicado em: 2018-02