Mostrando 1-12 de 48 artigos, teses e dissertações.
1. Prevalence and factors associated with metabolic syndrome in 6-10-year-old children
Abstract Aims: to identify the prevalence of metabolic syndrome (MetS) and associated risk factors in children. Methods: a total of 1,480 Brazilian children aged 6-10 years old (52.2% girls) participated in this population-based, epidemiological cross-sectional study. The inclusion criteria were children born between the years 2001 and 2006, of both sexe
Motriz: rev. educ. fis.. Publicado em: 03/12/2018
2. Liver metabolic changes induced by conjugated linoleic acid in calorie-restricted rats
ABSTRACT Objective Complexes like conjugated linoleic acid (CLA) reduce the percentage of body fat by increasing energy expenditure, fat oxidation, or both. The aim of this study was to verify if CLA is able to mimic caloric restriction (CR), and determine the effects of CLA on liver metabolic profile of young adult male Wistar rats. Materials and methods
Arch. Endocrinol. Metab.. Publicado em: 25/08/2016
3. Influência da restrição calórica no metabolismo bioenergético e estado redox de Saccharomyces cerevisiaee Kluyveromyces lactis / Influence of caloric restriction on energy metabolism and redox state of Saccharomyces cerevisiaee Kluyveromyces lactis
Aging involves a progressive decline in metabolic efficiency of biological systems over time. Although it cannot be avoided, aging phenotypes are delayed in organisms undergoing caloric restriction, a dietary regimen consisting of a reduced availability of calories. The yeast Saccharomyces cerevisiae has proved to be an important model organism for studying
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/01/2012
4. Failure of carnitine in improving hepatic nitrogen content in alcoholic and non-alcoholic malnourished rats
AIMS: To investigate the effect of carnitine supplementation on alcoholic malnourished rats' hepatic nitrogen content. METHODS: Malnourished rats, on 50% protein-calorie restriction with free access to water (malnutrition group) and malnourished rats under the same conditions with free access to a 20% alcohol/water solution (alcohol group) were studied. Afte
Clinics. Publicado em: 2010
5. Food restriction induces in vivo ventricular dysfunction in spontaneously hypertensive rats without impairment of in vitro myocardial contractility
Cardiac structures, function, and myocardial contractility are affected by food restriction (FR). There are few experiments associating undernutrition with hypertension. The aim of the present study was to analyze the effects of FR on the cardiac response to hypertension in a genetic model of hypertension, the spontaneously hypertensive rat (SHR). Five-month
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-04
6. Sir2 mediates longevity in the fly through a pathway related to calorie restriction
Calorie restriction can extend life span in a variety of species including mammals, flies, nematodes, and yeast. Despite the importance of this nearly universal effect, little is understood about the molecular mechanisms that mediate the life-span-extending effect of calorie restriction in metazoans. Sir2 is known to be involved in life span determination an
National Academy of Sciences.
7. Sir2-Independent Life Span Extension by Calorie Restriction in Yeast
Calorie restriction slows aging and increases life span in many organisms. In yeast, a mechanistic explanation has been proposed whereby calorie restriction slows aging by activating Sir2. Here we report the identification of a Sir2-independent pathway responsible for a majority of the longevity benefit associated with calorie restriction. Deletion of FOB1 a
Public Library of Science.
8. Calorie restriction extends yeast life span by lowering the level of NADH
Calorie restriction (CR) extends life span in a wide variety of species. Previously, we showed that calorie restriction increases the replicative life span in yeast by activating Sir2, a highly conserved NAD-dependent deacetylase. Here we test whether CR activates Sir2 by increasing the NAD/NADH ratio or by regulating the level of nicotinamide, a known inhib
Cold Spring Harbor Laboratory Press.
9. Calorie restriction suppresses subgenomic mink cytopathic focus-forming murine leukemia virus transcription and frequency of genomic expression while impairing lymphoma formation.
Calorie restriction suppresses mammary proviral mRNA expression and protooncogene activation in breast tumor-prone C3H/Ou mice while inhibiting tumor formation. To determine whether the beneficial effects of chronic energy-intake restriction (CEIR) can be extended to an organ site of retrovirus-induced tumorigenesis where the dynamics of growth and sexual ma
10. Low-calorie diet prevents the development of mammary tumors in C3H mice and reduces circulating prolactin level, murine mammary tumor virus expression, and proliferation of mammary alveolar cells
The effect of carlorie intake on the development of spontaneous mammary tumors in virgin C3H mice was studied. Only about 10% of the mice fed a low-calorie diet [10 kcal/day (1 kcal = 4.184 kJ)] since weaning developed mammary tumors, compared to about 60% of those mice that were reared on high-calorie diets (16 kcal/day or lab chow ad lib). In order to unde
11. Repeated binge access to a palatable food alters feeding behavior, hormone profile, and hindbrain c-Fos responses to a test meal in adult male rats
Repetitive cycles of palatable food access and chronic calorie restriction alter feeding behaviors and forebrain neural systems. The purpose of this study was to determine the behavioral, endocrine, and meal-related hindbrain neural activation in adult male Sprague-Dawley rats exposed to a binge-access feeding schedule. The binge-access schedule consisted of
American Physiological Society.
12. Inhibition by restricted-calorie diet of lymphoproliferative disease and renal damage in MRL/lpr mice.
Restriction of calorie intake from the time of weaning greatly prolongs life, and it inhibits development and expression of the lymphoproliferative syndrome, renal disease, and decline of certain immunologic functions with age in MRL/lpr mice. This dramatic influence of diet on mice of this short-lived autoimmunity-prone strain, while associated with decreas