Calcium Currents
Mostrando 1-12 de 744 artigos, teses e dissertações.
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1. Effect of iontophoresis on fluoride uptake in enamel with artificial caries lesion
Abstract: Iontophoresis is a noninvasive technique, based on the application of a constant low-intensity electric current to facilitate the release of a variety of drugs, whether ionized or not, through biological membranes. The objective of this research was to evaluate the effect of iontophoresis using different electric current intensities on the uptake o
Braz. oral res.. Publicado em: 16/05/2019
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2. Nitric oxide modulates ATP-evoked currents in mouse Leydig cells
Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and intracellular calcium storages recruited by a calcium-induced calcium release mechanism. On the other hand
Braz J Med Biol Res. Publicado em: 15/03/2018
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3. Cardiomyocyte dysfunction during the chronic phase of Chagas disease
Chagas disease, which is caused by the parasite Trypanosoma cruzi, is an important cause of heart failure. We investigated modifications in the cellular electrophysiological and calcium-handling characteristics of an infected mouse heart during the chronic phase of the disease. The patch-clamp technique was used to record action potentials (APs) and L-type C
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-04
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4. Augmentation of catecholamine release elicited by an Eugenia punicifolia extract in chromaffin cells
Plant extracts of Eugenia punicifolia (Kunth) DC., Myrtaceae, are used in Amazon region of Brazil to treat diarrhea and stomach disturbances, and as hypoglycemic medicine. We have recently shown that an aqueous extract of E. punicifolia augmented cholinergic neurotransmission in a rat phrenic nerve-diaphragm preparation. In this study, we investigated the ef
Revista Brasileira de Farmacognosia. Publicado em: 14/10/2011
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5. EFFECT OF AQUEOUS FRACTION OF LEAVES DE COSTUS SPIRALIS (JACQ.) ROSCOE CONTRACTILE FUNCTION ON HEART MAMMALS. / EFEITO DA FRAÇÃO AQUOSA DAS FOLHAS DE COSTUS SPIRALIS (JACQ.) ROSCOE SOBRE A FUNÇÃO CONTRÁTIL DO CORAÇÃO DE MAMÍFEROS.
Teas and infusions from C. spiralis leaf have largely been used by folk medicine as diuretic, hypotensor, cytotoxic, immunomodulator, antilithiasic, antidiarrheic, antispasmodic, antiurolitic, antimicrobian, antifungic, antioxidant, antileishmania activity, antiinflamatory, and antiedematogenic activity. In spite of these biological effects attributed to the
Publicado em: 2011
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6. A computer simulation study of motoneuron models with active dendrites in response to synaptic inputs. / Estudo por simulação computacional de modelos de motoneurônios com dendrito ativo em resposta a entradas sinápticas.
Mathematical models of motoneurons have been developed as an aid to the understanding of phenomena involving the neuromuscular system, but most of these models have been based on the hypothesis of a passive dendritic tree. This holds for anesthetized animals but not necessarily during normal motor behavior of the intact animal. Experiments with decerebrate a
Publicado em: 2010
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7. TMEM16 proteins: the long awaited calcium-activated chloride channels?
Currents mediated by calcium-activated chloride channels (CaCCs), observed for the first time in Xenopus oocytes, have been recorded in many cells and tissues ranging from different types of neurons to epithelial and muscle cells. CaCCs play a role in the regulation of excitability in neurons including sensory receptors. In addition, they are crucial mediato
Brazilian Journal of Medical and Biological Research. Publicado em: 25/09/2009
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8. Investigação do efeito vasorelaxante e caracterização eletrofisiológica dos alcalóides curina e reticulina
It was been demonstrated that curine and reticuline, induced a vasodilator effect in the rat small mesenteric arteries through inhibition of voltage-gated Ca2+ channels (VGCC). These compounds, curine and reticuline were isolated from the root barks of Chondrondendron platyphyllum and Ocotea duckei Vattimo, respectively, therefore the aim of this work was to
Publicado em: 2009
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9. Estudo das propriedades biofísicas e farmacológicas do poro associado ao receptors P2X7 e poros de características similares. / Study of the biophysical and pharmacological properties of the pore associated with receiver P2X7 and pores of similar characteristics.
The P2X7 receptor (EC50= ~100μM) induces cell membrane permeabilization to molecules up to 900 Da when activated by high ATP concentrations. So far, the correlation between the opening of low conductance cationic channel (8 pS) formed after stimulation with low ATP concentrations (EC50= ~1 μM) and the opening of P2X7 related pore is unclear. To dat
Publicado em: 2006
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10. The effect of wollastonite on operational characteristics of AWS E6013 electrodes
The main objective of this work was to assess the operational behavior of ANSI/AWS A5.1-91 E6013 type electrodes when 0, 8 and 16 % of quartz (100 % SiO2) is replaced with wollastonite (Calcium Silicate, 50 % SiO2 - 50 % CaO) in the coating composition. The electrodes were tested through bead-on-plate welds in flat position on DC, both polarities, and on AC
Journal of the Brazilian Society of Mechanical Sciences and Engineering. Publicado em: 2004-09
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11. Steps in the formation of neurites and synapses studied in cultured leech neurons
Leech neurons in culture have provided novel insights into the steps in the formation of neurite outgrowth patterns, target recognition and synapse formation. Identified adult neurons from the central nervous system of the leech can be removed individually and plated in culture under well-controlled conditions, where they retain their characteristic physiolo
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-05
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12. Mechanosensitivity of voltage-gated calcium currents in rat anterior pituitary cells.
Sensitivity of voltage-activated calcium currents to flow-induced mechanical stress was examined in enriched populations of rat anterior pituitary somatotrophs. Voltage-activated calcium currents were recorded with the whole-cell configuration of the patch-clamp technique. Pituitary cells were exposed to flow (from pipettes) which was produced by a hydrostat