Brain Diseases
Mostrando 1-12 de 445 artigos, teses e dissertações.
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1. Does Decreased SNX10 Serve as a Novel Risk Factor in Atrial Fibrillation of the Valvular Heart Disease? - A Case-Control Study
Abstract Introduction: Atrial fibrillation (AF) is the most common sustained arrhythmia. Sorting nexin 10 (SNX10) has been reported to be an important regulator in embryonic development and human diseases, however, little is known about its role in cardiac disease. The aim of this study was to investigate the clinical significance of SNX10 expression in AF.
Braz. J. Cardiovasc. Surg.. Publicado em: 2021-02
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2. Intestinal Microbiota and Cardiovascular Diseases
Abstract Recently, gut microbiota has emerged as an important mediator of several diseases such as diabetes, atherosclerosis, arterial hypertension, obesity, cancers and neuropsychiatric diseases including Alzheimer, autism and depression. Intestinal microbiota is formed by bacteria, fungi and viruses and its main function is to facilitate the absorption and
Int. J. Cardiovasc. Sci.. Publicado em: 2020-10
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3. The Gut Brain-Axis in Neurological Diseases
Abstract Recent evidence suggests that dysfunction of the gut-brain axis may be an important factor contributing to many diseases of the nervous system. Increased gut permeability associated with chronic gastrointestinal dysfunction, as well as changes in the composition of the gut microbiota could contribute to exposure of the enteric and central nervous sy
Int. J. Cardiovasc. Sci.. Publicado em: 2020-10
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4. Diosmin induces caspase-dependent apoptosis in human glioblastoma cells
Abstract: Diosmin is a flavone glycoside clinically used as the main component of Daflon for the treatment of venous diseases. Several studies demonstrated that this natural compound can induce apoptosis in different tumors. However, isolated diosmin has not been studied regarding its effects on glioblastoma so far. Since glioblastoma is a highly lethal and
An. Acad. Bras. Ciênc.. Publicado em: 02/12/2019
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5. Visual loss as first clinical manifestation of X-linked adrenoleukodystrophy
Resumo A adrenoleucodistrofia ligada ao X (X-ALD) representa um grupo de doenças caracterizadas pelo acúmulo de ácidos graxos de cadeia muito longa (VLCFAs) nos tecidos. Suas manifestações clínicas costumam ser múltiplas. Alterações visuais podem estar presentes, contudo costumam surgir mais tardiamente na doença. Descrevemos aqui o caso de um meni
Rev. bras.oftalmol.. Publicado em: 02/12/2019
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6. Déficits motores e preditores de perda de mobilidade ao final da internação em indivíduos com neurotoxoplasmose
RESUMO A neurotoxoplasmose (NTX) é uma das principais doenças oportunistas presentes em indivíduos portadores do vírus da imunodeficiência humana (HIV). A doença promove lesões cerebrais focais com efeito de massa que podem gerar uma variedade de sequelas capazes de comprometer a realização das atividades da vida diária, dentre elas, a deambulaçã
Fisioter. Pesqui.. Publicado em: 02/12/2019
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7. CHRONIC RESPONSES OF PHYSICAL AND IMAGERY TRAINING ON PARKINSON’S DISEASE
RESUMO Introdução Sabe-se que o treinamento físico e de imagética motora induz a resultados positivos na qualidade de vida dos pacientes com doenças neurodegenerativas. Entretanto, não se sabe quais efeitos são possíveis de se obter quando ambos tipos de treinamento são combinados. Objetivo O presente estudo teve como objetivo investigar os efei
Rev Bras Med Esporte. Publicado em: 11/11/2019
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8. Effects of Resistance Exercise with Instability on Neurocognitive Functions (REI STUDY): Study Protocol for a Proof-of-Concept Clinical Trial in Older Adults with Subjective Cognitive Complaints
Abstract Aim: Resistance exercise (RE) is a widely accepted strategy to counteract the effects of aging and chronic diseases on health-related outcomes. Studies have been suggested that RE improves brain and cognitive health. RE with unstable devices (REI) is a neuromotor complexity strategy with the potential to improve strength, power, and balance in onde
Motriz: rev. educ. fis.. Publicado em: 26/08/2019
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9. Leigh Syndrome Due to mtDNA Pathogenic Variants
Abstract Leigh syndrome is a devastating neurodegenerative disease, typically manifesting in infancy or early childhood. Hallmarks of the disease are symmetrical lesions in the basal ganglia or brain stem on MRI, and a clinical course with rapid deterioration of cognitive and motor functions. It is genetically heterogeneous, causative mutations have been dis
J. inborn errors metab. screen.. Publicado em: 05/08/2019
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10. Hormonal Biomarkers for Evaluating the Impact of Fetal Growth Restriction on the Development of Chronic Adult Disease
Resumo A hipótese das origens fetais de doenças em adultos propõe que distúrbios crônicos metabólicos, incluindo doenças cardiovasculares, diabetes e hipertensão, se originam na plasticidade do desenvolvimento devido a insultos intrauterinos. Estes processos envolvem uma resposta adaptativa do feto amudanças nos sinais ambientais que podem promover
Rev. Bras. Ginecol. Obstet.. Publicado em: 19/06/2019
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11. Hyperprolinemia Type IA: Benign Metabolic Anomaly or a Trigger for Brain Dysfunction?
Abstract Objective: Hyperprolinemia type I (HPI) is a rare and inherited autosomal recessive disorder caused by proline oxidase deficiency. Hyperprolinemia type 1 is biochemically defined as high plasma proline levels without urinary ?-1-pyrroline-5-carboxylate excretion. Hyperprolinemia type 1 has been considered a benign metabolic disorder, but a relation
J. inborn errors metab. screen.. Publicado em: 16/05/2019
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12. Mechanistic Bases of Neurotoxicity Provoked by Fatty Acids Accumulating in MCAD and LCHAD Deficiencies
Abstract Fatty acid oxidation defects (FAODs) are inherited metabolic disorders caused by deficiency of specific enzyme activities or transport proteins involved in the mitochondrial catabolism of fatty acids. Medium-chain fatty acyl-CoA dehydrogenase (MCAD) and long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiencies are relatively common FAOD bioche
J. inborn errors metab. screen.. Publicado em: 16/05/2019