Bone Morphogenetic Proteins
Mostrando 25-36 de 118 artigos, teses e dissertações.
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25. "Avaliação da osteogênese com proteínas ósseas morfogenéticas (BMPs): análise em defeitos na calvária e ao redor de implantes de titânio em coelhos". / Osseointegration enhancement around titanium implants and calvarial reconstruction induced by bone morphogenetic proteins in rabbits
Objective. Study I:The aim of this study was to assess osteogenesis in cirurgically created skull defects in rabbits (Oryctolagus cuniculus) induced by bone morphogenetic proteins combined to the composite calcium carboante-collagen. Study II: Avaliate osteogenesis around titanium implants inserted in the rabbit tibia, induced by bone morphogenetic protein c
Publicado em: 2002
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26. Bone morphogenetic proteins, genetics and the pathophysiology of primary pulmonary hypertension
Several recent papers have shown that both familial primary pulmonary hypertension (FPPH) and sporadic primary pulmonary hypertension (PPH) may have a common etiology that is associated with the inheritance and/or spontaneous development of germline mutations in the bone morphogenetic protein receptor (BMPR) type II gene. Because BMPR-II is a ubiquitously ex
BioMed Central.
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27. Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: noggin, chordin and DAN
This commentary is a concise discussion of the interactions between bone morphogenetic proteins (BMPs) and their binding proteins in bone and cartilage morphogenesis. BMPs are a family of growth and differentiation factors, and they act on mesenchymal cells to induce cartilage and bone differentiation in concentration-dependent thresholds. The BMP–BMP rece
BioMed Central.
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28. The extracellular regulation of bone morphogenetic protein signaling
In many cases, the level, positioning and timing of signaling through the bone morphogenetic protein (BMP) pathway are regulated by molecules that bind BMP ligands in the extracellular space. Whereas many BMP-binding proteins inhibit signaling by sequestering BMPs from their receptors, other BMP-binding proteins cause remarkably context-specific gains or los
Company of Biologists.
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29. Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals.
Both decapentaplegic (dpp) protein and 60A protein have been implicated in pattern formation during Drosophila melanogaster embryogenesis. Within the C-terminal domain, dpp and 60A are similar to human bone morphogenetic protein 2 (75% identity) and human osteogenic protein 1 (70% identity), respectively. Both recombinant human bone morphogenetic protein 2 a
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30. Bone morphogenetic proteins-2 and -4 are involved in the retinoic acid-induced differentiation of embryonal carcinoma cells.
Bone morphogenetic proteins-2 and -4 (BMPs-2 and -4) are transforming growth factor beta-related proteins that can induce bone formation in vivo. We observed that the level of endogenous BMP-2 mRNA increased an average of 11-fold on differentiation of F9 embryonal carcinoma cells into parietal endoderm after treatment with retinoic acid (RA) and cAMP, wherea
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31. A novel link between the proteasome pathway and the signal transduction pathway of the Bone Morphogenetic Proteins (BMPs)
BioMed Central.
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32. The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers.
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33. Drosophila 60A gene, another transforming growth factor beta family member, is closely related to human bone morphogenetic proteins.
The 60A gene, a member of the transforming growth factor beta superfamily of signaling proteins, has been identified in Drosophila melanogaster. From its inferred protein sequence we predict the precursor is secreted and processed to release a growth factor-like molecule. The 60A gene is expressed throughout development with peaks of transcription during ear
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34. Identification and characterization of cellular binding proteins (receptors) for recombinant human bone morphogenetic protein 2B, an initiator of bone differentiation cascade.
Bone morphogenetic protein 2B (BMP 2B), is a heparin-binding bone differentiation factor that initiates endochondral bone formation in rats when implanted subcutaneously. The molecular mechanism of action of this differentiation factor is not known, and as a first step we have examined BMP 2B-responsive cells for the presence of specific cellular binding pro
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35. Cloning and characterization of a human type II receptor for bone morphogenetic proteins.
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor beta superfamily. Several members of this family have been shown to transduce their signals through binding to type I and type II serine-(threonine) kinase receptors. Here we report the cDNA cloning and characterization of a human type II receptor for BMPs (BMPR-II), which is di
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36. A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.
Bone morphogenetic proteins (BMPs), which are members of the transforming growth factor beta (TGF-beta) superfamily, have been implicated in bone formation and the regulation of early development. To better understand the roles of BMPs in Xenopus laevis embryogenesis, we have cloned a cDNA coding for a serine/threonine kinase receptor that binds BMP-2 and BM