Bone Marrow Transplantation Immunology
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Dendritic cells and the 60kDa heat shock protein (Hsp60): strategies for immunoregulation in the mouse immune system / Células dendríticas e a proteína de choque térmico 60KDA (HSP60): estratégias para imunorregulação do sistema imune murino
The induction of tolerance to allotransplant without the help of immunosupressive drugs is one of the major challenges in immunology. Considering the tolerogenic potential of dendritic cells and the immunoregulatory activity of Hsp60, our objective was to determine the capacity of dendritic cells (DCs) of inducing immunoregulation through the interaction wit
Publicado em: 2008
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2. Avaliação da reconstituição imunológica e da resposta anti-citomegalovirus nos receptores de transplante de medula óssea / Anti-cytomegalovirus immunity reconstitution following autologous and allogeneic stem cell and bone marrow transplantation as assessed by CD8+ T cell phenotyping and functio
O citomegalovírus (CMV) é uma séria ameaça aos receptores de transplante de medula óssea. A reativação está associada com uma imunidade mediada por células TCD8+ defeituosa. Nosso objetivo foi correlacionar as diferentes subpopulações de células TCD8+ com a reconstituição imunológica dos pacientes, especificamente a imunidade anti-CMV, analisa
Publicado em: 2005
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3. Induction of allogeneic mixed chimerism by immature dendritic cells and bone marrow transplantation leads to prolonged tolerance to major histocompatibility complex disparate allografts
Mixed chimerism has been shown to lead to prolonged major histocompatibility complex (MHC) disparate allograft survival and immune-specific tolerance; however, traditional conditioning regimes often involve myeloablation, which may pose a significant safety risk. In this study we examined the use of donor C57BL/6 (H-2b) immature dendritic cells (imDCs) to to
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