Bmp 7
Mostrando 13-24 de 121 artigos, teses e dissertações.
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13. O que há de novo em genética e classificação de osteogênese imperfeita?
OBJETIVO: Revisão da literatura sobre novos genes relacionados à osteogênese imperfeita (OI) e atualização da sua classificação. FONTE DOS DADOS : Revisão nas bases de dados do PUBMED e OMIM com seleção de referências relevantes. SÍNTESE DOS DADOS: Sillence et al., em 1979, desenvolveram uma classificação dos subtipos de OI baseada em
J. Pediatr. (Rio J.). Publicado em: 2014-12
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14. Cranial vault reconstruction with bone morphogenetic protein, calcium phosphate, acellular dermal matrix, and calcium alginate in mice
PURPOSE: To evaluate experimental cranial vault reconstructions, by combining bone morphogenetic protein type 2 (BMP-2) and different matrices.
METHODS: Fourty-nine animals were initially included (seven per group). We designed an experimental, open, prospective and comparative study, divided in seven gro
Acta Cir. Bras.. Publicado em: 2014-10
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15. BMP-2 and titanium particles synergistically activate osteoclast formation
A previous study showed that BMP-2 (bone morphogenetic protein-2) and wear debris can separately support osteoclast formation induced by the receptor activator of NF-κB ligand (RANKL). However, the effect of BMP-2 on wear debris-induced osteoclast formation is unclear. In this study, we show that neither titanium particles nor BMP-2 can induce osteoclast fo
Braz J Med Biol Res. Publicado em: 2014-06
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16. Effects of GDF-9 and FSH on mRNA expression for FSH-R, GDF-9 and BMPs in in vitro cultured goat preantral follicles
The aim of the present study was to determine the role of GDF-9 and/or FSH on the growth and mRNA expression for FSH-R, GDF-9, and BMPs in goat secondary follicles after culture in vitro. Goat secondary follicles (~200µm) were isolated and cultured for six days in minimum essential medium (MEM) supplemented with GDF-9 (200 ng/mL), FSH (50 ng/mL) or both. At
Braz. arch. biol. technol.. Publicado em: 2014-04
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17. Adenovirus-mediated siRNA targeting TNF-α and overexpression of bone morphogenetic protein-2 promotes early osteoblast differentiation on a cell model of Ti particle-induced inflammatory response in vitro
Wear particles are phagocytosed by macrophages and other inflammatory cells, resulting in cellular activation and release of proinflammatory factors, which cause periprosthetic osteolysis and subsequent aseptic loosening, the most common causes of total joint arthroplasty failure. During this pathological process, tumor necrosis factor-alpha (TNF-α) plays a
Braz J Med Biol Res. Publicado em: 2013-10
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18. Efeito in vitro da triiodotironina sob o potencial osteogênico reduzido de células-tronco mesenquimais do tecido adiposo de ratas ovariectomizadas e com osteoporose
OBJETIVO: Avaliar se a triiodotironina (T3) aumenta a diferenciação osteogênica das células-tronco mesenquimais do tecido adiposo (CTM-TA) de ratas adultas ovariectomizadas e com osteoporose e compará-lo ao de ratas adultas e jovens sem osteoporose. MATERIAIS E MÉTODOS: CTM-TA foram cultivadas em meio osteogênico e distribuídas em sete grupos: 1) CTM
Arq Bras Endocrinol Metab. Publicado em: 2013-03
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19. Análise de genes diferencialmente expressos nas vias de sinalização (Hedgehog e Wnt) em carcinomas basocelulares humanos
Hedgehog (HH) and Wingless-Int (Wnt) signaling pathway are related to the process of cellular proliferation, differentiation, angiogenesis, matrix remodeling and homeostasis of stem cells. Over the years, several mutations in HH signaling pathway have been identified, including the loss of function mutations in ptch1 and the gain of function mutations in smo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/04/2012
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20. Análise do mRNA da proteína BMP-15 e IGF-2 em oócitos e células do cumulus de ovelhas do semiárido pernambucano. / Analysis of mRNA expression of BMP-15 and IGF-2 proteins in oocytes and cumulus cells of sheep in semi-arid state of Pernambuco.
Two experiments were conducted to analyze the expression of genes related to follicular development and subsequent reproductive efficiency in oocytes and cumulus cells in two distinct phases of folliculogenesis. Ovaries of native breeds of sheep slaughtered in the abattoir in Caruaru/PE were collected and transported to the Laboratory of Applied Molecular An
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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21. Efeito da anodização com CaP em superfícies de titânio sobre a resposta de osteoblastos
O objetivo deste estudo foi investigar a influência da anodização com incorporação de CaP em superfícies de titânio no processo de osteogênese in vitro. Para tanto, osteoblastos humanos da linhagem hFOB 1.19 foram plaqueados sobre discos de titânio comercialmente puro (8x4 mm) com três tratamentos de superfície (n=21 discos/grupo): usinado (Screw)
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2012
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22. Addition of bone morphogenetic protein type 2 to ascorbate and β-glycerophosphate supplementation did not enhance osteogenic differentiation of human adipose-derived stem cells
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. OBJECTIVES: This study evaluated the effect of a recombinant BMP-2 as well as the endogenous BMP-4 and BMP-7 in the osteogenic differentiation of adipose-derived stem cells (ASCs) in mediu
J. Appl. Oral Sci.. Publicado em: 2012-12
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23. Tissue transglutaminase (TG2) activity regulates osteoblast differentiation and mineralization in the SAOS-2 cell line
Tissue transglutaminase (type II, TG2) has long been postulated to directly promote skeletal matrix calcification and play an important role in ossification. However, limited information is available on the expression, function and modulating mechanism of TG2 during osteoblast differentiation and mineralization. To address these issues, we cultured the well-
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-08
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24. Avaliação histológica e imunolocalização de STRO-1 e BMP-4 em molares de ratos com polpa vital ou necrose pulpar induzida durante o desenvolvimento radicular
Objective: the aim of this study was to characterize the features of live and necrotic dental pulps of molar teeth in rats with developing roots, and to assess the expression of STRO-1 and BMP-4. Methods: twenty-four 4-month-old male Wistar rats were used. To induce necrosis, the pulps of the first lower left molars were exposed to the oral environment. The
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012