Blood Coagulation Factors
Mostrando 13-24 de 77 artigos, teses e dissertações.
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13. Triple bothropic envenomation in horses caused by a single snake
In the present study, snakebites caused by a single Bothrops pauloensis simultaneously affecting three male adult horses are described. Whereas the first two affected horses were six years old, the third was 16 years old; they weighed respectively 555, 550 and 500 kg. All horses presented swollen muzzles. The first animal received an initial antivenom dose o
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2011
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14. Estudo da hemostasia em pacientes submetidas a cirurgias plasticas com e sem antecedentes de gastroplastia redutora / Study of hemostasis in pacients undergoing plastic surgery procedures with and without a history of weight reducing by gastroplasty
Plastic surgery procedures performed in patients who previously underwent weight reducing gas troplasty present a high risk for medical complications, one of the most severe being bleeding during the perioperative period. Although the cause of this bleeding is currently unknown, it is postulated that these patients may present alterations in hemostasis not d
Publicado em: 2009
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15. Avaliação da atividade fibronolitica oral em pacientes sob anticoagulação oral / Evaluation of oral fibrinolytic activity of patients under oral anticoagulation
Fibrinolysis is a part of the haemostatic process that is responsible for reestablish the blood flow, by the dissolution of the fibrin clot formed after a vascular injury. This process can be altered by several factors, such as tissue trauma and presence of inflammatory or infectious process, which can increase the local fibrinolytic activity and, by that, c
Publicado em: 2009
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16. Evaluation of prothrombotic and proinflammatory factors in Chagas cardiomyopathy / Estudo de fatores protrombóticos e proinflamatórios na cardiomiopatia chagásica
Fundamento: A ativação da cascata inflamatória está presente na insuficiência cardíaca(IC). Existe relação entre esta ativação e estado protrombótico nesta síndrome. Dentre as etiologias de IC, a cardiomiopatia chagásica (CMC) parece ter maior ativação inflamatória e prognóstico mais reservado, possivelmente por especial risco para fenômeno
Publicado em: 2009
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17. Animais transgênicos utilizados como biorreatores
The increasing demand for production of pharmaceutical interest recombinant proteins has been the goal for the development of additional systems to its production on a large scale and reduced costs. Eukaryotes expression systems are possible alternatives to the production of recombinant protein (Leite, 2000). The secretion of these polypeptides in the milk o
Publicado em: 2008
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18. The clinical impact of MTHFR polymorphism on the vascular complications of sickle cell disease
Sickle cell disease (SCD) is one of the most common inherited diseases in the world and the patients present notorious clinical heterogeneity. It is known that patients with SCD present activation of the blood coagulation and fibrinolytic systems, especially during vaso-occlusive crises, but also during the steady state of the disease. We determined if the p
Brazilian Journal of Medical and Biological Research. Publicado em: 09/08/2006
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19. Novel role of antiplatelet agents (aspirin plus clopidogrel) in an incoagulable blood of a victim of russell's viper snakebite
Snake antivenom is a specific antidote to the venom action, neutralizing the circulating venom. However, it fails to neutralize the venom fixed to target organs such as platelets, renal tubules, etc. Russell's viper venom initiates rapid coagulation in a victim by activating blood platelets, factors V, X, and anticoagulant cofactors. Activation of thrombin,
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2006
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20. Fibrinogenio, FVII, FVIII, FIX, FX e FXI como fatores de risco para tromboembolismo venoso em pacientes de uma população brasileira / Fibrinogen, FVII, FVIII, FIX, FX and FXI as risk factors for venous throembolism among patients of a Brazilian population
Nos últimos anos tem sido demonstrada uma associação entre níveis elevados de certos fatores da coagulação e risco de tromboembolismo venoso (TEV). Entretanto, o número de estudos é pequeno e a maioria estão restritos a populações caucasóides. Neste estudo caso-controle emparelhado por idade, sexo e etnia investigamos os níveis plasmáticos do f
Publicado em: 2006
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21. Blood coagulation and its alterations in hemorrhagic and thrombotic disorders.
Clinical observations have added to the understanding of basic mechanisms of blood coagulation and its alterations in certain hemorrhagic and thrombotic states. Much clinical evidence exists for concluding that the exposure of blood to tissue factor (thromboplastin) on tissue cells represents the key event initiating fibrin clot formation after tissue injury
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22. Endotoxin-induced pulmonary dysfunction is prevented by C1-esterase inhibitor.
In septic shock, hypotension, disseminated intravascular coagulation, and neutrophil activation are related to the activation of the blood coagulation contact system. This study evaluates in dogs the effect of the C1-esterase inhibitor (C1-INH), a main inhibitor of the blood coagulation contact system, on the cardiovascular and respiratory dysfunction associ
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23. Coagulation cascade in sepsis: getting from bench to bedside?
The relationship between blood coagulation factors and the promotion or inhibition of the anti-inflammatory response continues to be defined through basic research. The potential key role of blood coagulation factors in the response during sepsis provides an exciting potential mechanism(s) for modification through the application of new therapies. The comple
BioMed Central.
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24. Release of β-Lysin from Platelets by Thrombin and by a Factor Produced in Heparinized Blood
Removal of calcium by either citrate, oxalate, or ethylenediaminetetraacetate inhibited coagulation of blood at an early stage and prevented the release of β-lysin from platelets. In contrast, heparin caused platelet agglutination and stimulated β-lysin release in vitro and in vivo. This release was calcium dependent and may have been due to a calcium-depe