Biological Interactions
Mostrando 1-12 de 917 artigos, teses e dissertações.
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1. A New Synthetic Route and Comprehensive Topological Study of a Benzimidazole Derivative
Benzimidazole and its derivatives are molecules that have diverse biological properties, therefore we synthesized and studied a new benzimidazole to understand their physical/chemical properties. The compound was obtained through a new synthetic route, using graphite oxide, in the absence of solvent, with crystalline packaging supported by C-H…N and C-H…
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Flumioxazin, imazethapyr and their mixture in the rhizosphere of soybean: effect on early nodulation and biological N fixation
ABSTRACT The application of flumioxazin and imazethapyr can affect the interactions between rhizobia and soybean in the rhizosphere. However, it remains unclear the effect of both herbicides, even when applied in mixture, on early nodulation and biological N fixation (BNF) in soybean, mainly related to some important biochemical traits in nodules. This study
Revista Ceres. Publicado em: 2022
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3. BIOMARCADORES MOLECULARES DE DOENÇAS HUMANAS: CONCEITOS FUNDAMENTAIS, MODELOS DE ESTUDO E APLICAÇÕES CLÍNICAS
Molecular biomarkers correspond to all endogenous or exogenous biomolecules, whose presence or alteration in metabolic pathways indicate the response of a biological system to a disturbance caused by internal or external factors. The search for biomarkers has allowed deepening the knowledge of complex pathophysiological mechanisms of diseases, interactions w
Química Nova. Publicado em: 2022
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4. A IMPORTÂNCIA DAS CUMARINAS PARA A QUÍMICA MEDICINAL E O DESENVOLVIMENTO DE COMPOSTOS BIOATIVOS NOS ÚLTIMOS ANOS
Coumarins are natural products characterized as 2H-chromen-2-one, according to IUPAC nomenclature, largely distributed in plants, as well as, in species of fungi and bacteria. Nowadays, many synthetic procedures allow the discovery of coumarins with expanded chemical space. The ability to exert non-covalent interactions with many enzymes and receptors in liv
Quím. Nova. Publicado em: 2021-02
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5. EXTRACTION OF MONOMERS OF HYDROLYSABLE TANNINS FROM PODS OF Libidibia ferrea (Mart. ex Tul.) L. P. QUEIROZ: EFFECTS OF SOLVENT AND AMOUNT OF DRUG USING RESPONSE-SURFACE METHODOLOGY AND DESIRABILITY PROFILE
In this study was evaluated the influence of the extraction factors on the extract’s properties to improve the recovery of high concentrations of the phytochemicals important for the biological activities from pods of Libidibia ferrea (Mart. ex Tul.) L. P. Queiroz. The extracts were obtained by turbo-extraction and a factorial design 32 was used to study t
Quím. Nova. Publicado em: 2020-06
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6. Crystal Structure and 1H NMR Experimental and Theoretical Study of Conformers of 5-Methyl-1-(4’-methylphenylsulfonylamino)-1H-[1,2,3]-triazole-4-carboxylic Acid Ethyl Ester and 5-Methyl-1-(phenylsulfonylamino)-1H-[1,2,3]-triazole-4-carboxylic Acid Ethyl Ester
We reported experimental and theoretical investigation of conformers of 1,2,3-triazole derivatives, substances of exclusively synthetic origin, subject of extensive studies, because of several biological properties, such as antiviral, antimicrobial and antileishmaniasis. We reported molecular/supramolecular X-ray structures of antiophidian compounds I and II
J. Braz. Chem. Soc.. Publicado em: 2020-05
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7. ABRINDO A CAIXA DE PANDORA DOS NANOMEDICAMENTOS: HÁ REALMENTE MUITO MAIS ‘ESPAÇO LÁ EMBAIXO’
Limitations of conventional treatment and dosage forms prompted the investigation of novel approaches that combine efficacy, selectivity and fewer adverse effects. These are the main promises of nanomedicine, generally defined as the application of nanotechnology to the biomedical field. Despite the considerable advances over the years and the large number o
Quím. Nova. Publicado em: 2020-02
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8. Trends and Predictors of Oral Anticoagulation in Patients with Atrial Fibrillation: A Serial Cross-Sectional Study from 2011 to 2016
Abstract Background: Despite the efficacy of vitamin K antagonists against stroke in patients with atrial fibrillation (AF), the underuse of this therapy is well documented. Objectives: To evaluate trends and predictors of oral anticoagulants utilization in patients with AF. Methods: Observational, retrospective, serial cross-sectional study between 2011-
Int. J. Cardiovasc. Sci.. Publicado em: 2020-02
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9. Asymmetric intraguild predation of Harmonia axyridis (Pallas, 1773) (Coleoptera: Coccinellidae) on a native Coccinellidae guild
Abstract Harmonia axyridis is an exotic species that can cause serious impacts on native biodiversity in areas where it is introduced to act as a biological control agent. This predator is often involved with intraguild predation, in most cases with aphids predators. Here, we report the results of experiments designed to understand the outcome of the invasio
Rev. Bras. entomol.. Publicado em: 17/01/2020
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10. In Silico Target Identification and Validation for Antioxidant and Anti-inflammatory Activity of Selective Phytochemicals.
Abstract Phytochemicals present in plant extract include a number of biological active compounds which have shown promising antioxidant and anti-inflammatory activities in many animal studies. Present knowledge about the biochemical interactions of these compounds present in phytochemical extracts and target enzymes or proteins responsible for antioxidant an
Braz. arch. biol. technol.. Publicado em: 20/12/2019
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11. (Bio)conjugation Strategies Applied to Fluorescent Semiconductor Quantum Dots
Quantum dots (QDs) are semiconductor nanocrystals, which present unique photophysical properties, enabling their application as new fluorescent platforms for biomedical sciences. Colloidal QDs are end-capped with organic or inorganic compounds, not only to prevent their agglomeration but also to provide reaction sites for the attachment of targeting (bio)mol
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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12. Trends and Predictors of Oral Anticoagulation in Patients with Atrial Fibrillation: A Serial Cross-Sectional Study from 2011 to 2016
Abstract Background: Despite the efficacy of vitamin K antagonists against stroke in patients with atrial fibrillation (AF), the underuse of this therapy is well documented. Objectives: To evaluate trends and predictors of oral anticoagulants utilization in patients with AF. Methods: Observational, retrospective, serial cross-sectional study between 2011-
Int. J. Cardiovasc. Sci.. Publicado em: 24/10/2019