Binding Effect
Mostrando 1-12 de 7526 artigos, teses e dissertações.
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1. In vitro degradative effect of purified zearalenone with or without adsorbents after bionic digestion
Abstract The occurrence of zearalenone is considered a major risk factor affecting human and animal health worldwide. Zearalenone-contaminated feed can cause serious disorders and diseases in farm animals. A number of approaches have been developed to counteract zearalenone, but only few can be used. A potential approach to protecting animals against the har
Food Sci. Technol. Publicado em: 2021-09
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2. Allyl Dibenzoylmethane Derivative: Antimelanoma Activity and Study of Its Molecular Mechanism of Interaction with DNA
In this study, we assessed the cytotoxic effect of 1,3-diphenyl-2-allyl-1,3-propanedione (DPAP) on B16F10 and Tm5 melanoma cells and investigated its interaction with DNA (deoxyribonucleic acid) using optical tweezers. The compound showed to be effective against B16F10 cells with selectivity index (SI) of 7.92 and interaction to the outer surface of the doub
J. Braz. Chem. Soc.. Publicado em: 2021-07
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3. Dolomite-zirconia reaction sintered bonded coarse magnesia ceramics: effect of the bonding proportion
Abstract Refractory ceramic materials were manufactured, mainly composed of magnesia grains (coarse and medium fraction) and CaZrO3/MgO as a binding phase produced from the reaction sintering between CaMg(CO3)2 (dolomite) and m-ZrO2 (monoclinic zirconia), which constituted the finer fraction. Different relationships between the proportion and the size of the
Cerâmica. Publicado em: 2021-06
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4. Inhibitory effects of L-3-phenyllacitc acid on the activity of mushnroom pholyphenol oxidase
Abstract Polyphenol oxidase is the popular enzyme involved in fruit-vegetable browning and melanin synthesis. In the present paper, L-3-phenyllactic acid, a natural bacteriostatic substance, was investigated as an inhibitor of polyphenol oxidase. The results were demonstrated that the residual enzyme activity of polyphenol oxidase decreased gradually with th
Food Sci. Technol. Publicado em: 2021-06
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5. Effect of molecular weight on hypolipidemic and hypoglycemic activities of fermented Auriculaia auricula supernatant
Abstract Auriculaia auricula is considered as species of Mu Er in Chinese medicine and today are used interchangeably. A. auricula polysaccharides have been shown anti-cholesterol and anti-hyperglycemia. The aim of this research was to investigate the hypolipidemic and anti-hyperglycemic effects of extracts from different molecular weight fragments of A. aur
Food Sci. Technol. Publicado em: 2020-06
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6. Editar Machado de Assis
In this work, a systematic study of 17α-ethinylestradiol and estrone molecules interacting with single wall carbon nanotube is presented by means of first principle calculations. The structural properties, binding energy, charge transfer, and electronic properties were calculated and analyzed to characterize the effect of interaction of 17α-ethinylestradio
Machado Assis Linha. Publicado em: 2020-04
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7. Ab initio Study of 17α-Ethinylestradiol and Estrone Molecules Interacting with Single Wall Carbon Nanotube
In this work, a systematic study of 17α-ethinylestradiol and estrone molecules interacting with single wall carbon nanotube is presented by means of first principle calculations. The structural properties, binding energy, charge transfer, and electronic properties were calculated and analyzed to characterize the effect of interaction of 17α-ethinylestradio
J. Braz. Chem. Soc.. Publicado em: 2020-04
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8. Co-transfection of hepatocyte growth factor and truncated TGF-β type II receptor inhibit scar formation
Wound scarring remains a major challenge for plastic surgeons. Transforming growth factor (TGF)-β plays a key role in the process of scar formation. Previous studies have demonstrated that truncated TGF-β type II receptor (t-TGF-βRII) is unable to continue signal transduction but is still capable of binding to TGF-β, thereby blocking the TGF-β signaling
Braz J Med Biol Res. Publicado em: 2020-01
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9. Icariin stimulates differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs) through activation of cAMP/PKA/CREB
Icariin, a prenylated flavonol glycoside isolated from Epimedium, has been considered as a potential alternative therapy for osteoporosis. The present study aimed to clarify the detailed molecular mechanisms of action of icariin on osteoblast function, using bone marrow-derived mesenchymal stem cells (BM-MSCs). BM-MSCs were first stimulated by icariin. Then,
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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10. Therapeutic effects of dimethyldiguanide combined with clomifene citrate in the treatment of polycystic ovary syndrome
RESUMO OBJETIVO Tendo em vista a alta incidência de síndrome dos ovários policísticos (SOP) e os efeitos terapêuticos insatisfatórios da dimetildiguanida ou do citrato de clomifeno isoladamente, nosso estudo teve como objetivo investigar os efeitos terapêuticos da dimetildiguanida associada ao citrato de clomifeno no tratamento da SOP. MÉTODOS Um
Rev. Assoc. Med. Bras.. Publicado em: 10/10/2019
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11. Phenotypic correlation of characteristics in the gilt performance test with an average number of live-born piglets through all achieved births, during the reproductive exploitation
RESUMO A eficácia reprodutiva das porcas dita o nível de rentabilidade da própria produção, e o momento do teste e seleção de leitoas para reprodução (como os pais de uma geração futura) representa um momento muito importante. Dado o fato de que a seleção de leitoas para criação é parcialmente baseada no ganho de peso no teste, neste estudo e
Arq. Bras. Med. Vet. Zootec.. Publicado em: 10/10/2019
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12. LIPIDS AS COMPETITIVE INHIBITORS OF SUBTILISIN CARLSBERG IN THE ENZYMATIC HYDROLYSIS OF PROTEINS IN RED TILAPIA (Oreochromis sp.) VISCERA: INSIGHTS FROM KINETIC MODELS AND A MOLECULAR DOCKING STUDY
Abstract Protein hydrolysis can improve food’s nutritional, techno-functional and biological properties, which can increase the possibilities of application in industry. The objective of this research article was to study the effect of lipids on the enzymatic kinetics of red tilapia viscera (RTV) hydrolysis with subtilisin Carlsberg. The RTV were hydrolyze
Braz. J. Chem. Eng.. Publicado em: 30/09/2019