Biflavonoids
Mostrando 13-18 de 18 artigos, teses e dissertações.
-
13. Dímeros flavônicos bioativos de Ouratea multiflora (Ochnaceae)
Chromatographic fractionation of the organic extract from leaves of Ouratea multiflora afforded the flavone dimers heveaflavone, amentoflavone-7¢¢,4¢¢¢-dimethyl eter, podocarpusflavone-A and amentoflavone. Their structures were elucidated from spectral data, including 2D-NMR experiments of the natural su
Revista Brasileira de Farmacognosia. Publicado em: 2007-09
-
14. Biodiversidade flavonoídica e aspectos farmacológicos em espécies dos gêneros Ouratea e Luxemburgia (Ochnaceae)
This work describes the flavonoids and biflavonoids found in species of Ouratea and Luxemburgia as chemical markers that serve to detect the difference between these taxa according to the linkage between the flavonoidal units. A rational nomenclature is proposed and the pharmacological potencial is discussed.
Química Nova. Publicado em: 2007-08
-
15. Imunomodulação e ação anti-Leishmania (Viannia) braziliensis por Ouratea cuspidata (Ochnaceae) / Immunomodulation and action anti-Leishmania (Viannia) braziliensis promastigotes by Ouratea cuspidata (Ochnaceae)
Ouratea cuspidata (Ochnaceae) crude extracts were added to experimental systems containing either host macrophages, or Leishmania braziliensis promastigotes (L566). The biological effect by the use of the hexane (OCH), methanol (OCMeH) and ethyl-acetate (OCAcEt) extracts added at different concentrations: 2mg/mL; 4mg/mL; 8mg/mL, 16mg/mL e 32mg/mL. The OCMeOH
Publicado em: 2007
-
16. Biflavonoids and other phenolics from Caesalpinia pyramidalis (Fabaceae)
O reestudo do extrato clorofórmico das folhas de Caesalpinia pyramidalis (Caesalpinioidea, Fabaceae) forneceu, além do novo biflavonóide denominado caesalflavona, podocarpusflavona A, agathisflavona, apigenina, kaempferol, sitosterol e lupeol. Por outro lado, a partir do extrato clorofórmico do caule foram obtidos 4, 4'-diidroxi-2'-metoxi-chalcona, (-)-s
Journal of the Brazilian Chemical Society. Publicado em: 2005-11
-
17. DNA topoisomerase inhibitors: biflavonoids from Ouratea species
Topoisomerase inhibitors are agents with anticancer activity. 7"-O-Methyl-agathisflavone (I) and amentoflavone (II) are biflavonoids and were isolated from the Brazilian plants Ouratea hexasperma and O. semiserrata, respectively. These biflavonoids and the acetyl derivative of II (IIa) are inhibitors of human DNA topoisomerases I at 200 µM, as demonstrated
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-07
-
18. Biflavonoids inhibit the production of aflatoxin by Aspergillus flavus
The biflavonoids 6,6"-bigenkwanin, amenthoflavone, 7,7"-dimethoxyagastisflavone and tetradimethoxybigenkwanin isolated from Ouratea species were tested for inhibitory activity on Aspergillus flavus cultures. Suspensions of Aspergillus flavus spores were inoculated into 50 ml of YES medium at different biflavonoid concentrations: 5 and 10 µg/ml for 6,6"-bige
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-11