Beta Lactamase Ctx M
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Resistance patterns, ESBL genes, and genetic relatedness of Escherichia coli from dogs and owners
Abstract Antimicrobial resistance in Escherichia coli isolated from pet dogs can be considered a potential threat of infection for the human population. Our objective was to characterize the resistance pattern, extended spectrum beta-lactamase production and genetic relatedness of multiresistant E. coli strains isolated from dogs (n = 134), their owners (n =
Braz. J. Microbiol.. Publicado em: 2016-03
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2. Phenotypic and molecular characterization of CTX-M extended-spectrum beta-lactamase-producing Escherichia coli isolates in Shiraz, Iran
AbstractINTRODUCTIONThe aim of this study was to detect the prevalence of the extended-spectrum beta-lactamase (ESBL)-encoding CTX-M gene in Escherichia coliisolates.METHODS:Phenotypic screening of 376 E. coli isolates for ESBL was conducted using disk diffusion. ESBL-producing isolates were tested using PCR and specific primers. The blaCTX-M cluster was ide
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-08
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3. Extended-spectrum beta-lactamase-producing bacteria isolated from hematologic patients in Manaus, State of Amazonas, Brazil
Antibiotic therapy in hematologic patients, often weak and susceptible to a wide range of infections, particularly nosocomial infections derived from long hospitalization periods, is a challenging issue. This paper presents ESBL-producing strains isolated from such hematologic patients treated at the Amazon Hematology and Hemotherapy Foundation (HEMOAM) in t
Brazilian Journal of Microbiology. Publicado em: 2011-09
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4. Prevalência de beta-lactamases de amplo espectro e metilases RNAr 16S em isolados clínicos de Pseudomonas aeruginosa multirresistentes recuperados em diferentes hospitais de São Paulo / Prevalence of Extended-spectrum beta-lactamase and 16S rRNA methylases in clinical isolates of multidrug-resistant Pseudomonas aeruginosa recovered from differents hospitals in São Paulo
Introduction and aim: The production of extended-spectrum beta-lactamases (ESBLs) has been restricted to Klebsiella spp. and Escherichia coli, being associated with high rates of resistance, morbidity and mortality. Since genetic determinants for ESBLs (blaESBL genes) are mediated by plasmids, the spread to other medical important species is considered an ep
Publicado em: 2009
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5. Epidemiologia molecular de Escherichia coli e Klebsiella spp produtoras de beta-lactamase de espectro ampliado
The extended-spectrum beta-lactamases (ESBL) represent an important mechanism of resistance to beta-lactam antibiotics. Such enzymes have spread among members of the Enterobacteriaceae family, which are responsible for infections related to health care, particularly nosocomial infections. Objectives: (a) To determine the prevalence of ESBL producing Escheric
Publicado em: 2009
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6. Klebsiella pneumoniae: estudo molecular dos fatores de resistÃncia e caracterizaÃÃo ultra-estrutural da aÃÃo de antibiÃticos β-lactÃmicos
Klebsiella pneumoniae is an enterobacteria responsible for a high incidence of hospital infections usually caused by strains carrier of multidrug resistance and producer of broad spectrum -lactamase (ESBL). This study aimed to determine the genes involved in the formation of classical beta-lactamases and ESBLs in Recife-PE, Brazil, and investigate th
Publicado em: 2009
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7. [Beta]-lactamases na família enterobacteriaceae : métodos de detecção e prevalência
Entre membros da Família Enterobacteriaceae a produção de β-lactamases de espectro estendido (ESBL – Extended-Spectrum β-lactamase) se constitui em um importante mecanismo de resistência a antibióticos β-lactâmicos. O objetivo deste estudo foi determinar a prevalência de ESBL em diferentes gêneros da Família Enterobacteriaceae em um hospital un
Publicado em: 2008
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8. Caracterização molecular de genes blaCTX-M presentes em Klebsiella spp. isoladas em hospital universitário do Brasil / Molecular characterization of blaCTX-M genes found in Klebsiella spp. isolated in brazilian university hospital
Entre as ß-lactamases, as enzimas CTX-M têm despertado atenção especial pela alta incidência e grande capacidade de propagação. Eventos como recombinação gênica, transferência plasmideal e multirresistência podem ser a razão da manutenção e da ampla disseminação dos genes blaCTX-M. Este é um trabalho retrospectivo que teve como objetivo car
Publicado em: 2007
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9. Genotypic characterization of extended-spectrum beta-lactamase-producing Enterobacteriaceae strains, isolated from patients of a public hospital in the city of São Paulo. / Caracterização genotípica de cepas da família enterobacteriaceae produtoras de ß-lactamases de espectro estendido, isoladas de pacientes de um hospital da rede pública da cidade de São Paulo.
Introdução - A crescente resistência antimicrobiana em bactérias responsáveis por infecções hospitalares é um grande desafio à Saúde Pública. as B-lactamases de espectro estendido (ESBL), que hidrolisam a maioria dos compostos B-lactâmicos, são reconhecidas mundialmente como um grande problema para pacientes hospitalizados, devido à localizaç�
Publicado em: 2006
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10. Sequences of beta-lactamase genes encoding CTX-M-1 (MEN-1) and CTX-M-2 and relationship of their amino acid sequences with those of other beta-lactamases.
Amino acid sequences determined either by protein sequencing or by DNA sequencing are identical for cefotaximases CTX-M-1 and MEN-1, whereas CTX-M-2 is 84% identical to CTX-M-1/MEN-1. Both beta-lactamases are distantly related to other plasmidic class A enzymes (homology to TEM-1 is 38.1% for CTX-M-1/MEN-1 and 36.5% for CTX-M-2); the closest relationship was
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11. Dissemination of the novel plasmid-mediated beta-lactamase CTX-1, which confers resistance to broad-spectrum cephalosporins, and its inhibition by beta-lactamase inhibitors.
The novel beta-lactamase CTX-1 (pI 6.3) encoded on a transferable 84-kilobase plasmid was found in six different bacterial species. It was responsible for a significant decrease in susceptibility towards most penicillins and cephalosporins, except imipenem, temocillin, and cephalosporins which have a 7-alpha-methoxy substituent. Synergy between either ampici
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12. Comparative study of a novel plasmid-mediated beta-lactamase, CAZ-2, and the CTX-1 and CAZ-1 enzymes conferring resistance to broad-spectrum cephalosporins.
Infections caused by strains of Klebsiella pneumoniae resistant to broad-spectrum cephalosporins have been observed recently in hospitals in Clermont-Ferrand, France. beta-Lactam resistance resulted primarily from the plasmid-mediated, expanded-spectrum CTX-1 beta-lactamase. Furthermore, since 1987 some K. pneumoniae isolates more resistant to ceftazidime th