Beta Adrenergic Agonist
Mostrando 1-12 de 225 artigos, teses e dissertações.
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1. Determination of Mirabegron in rat plasma by UPLC–MS/MS after oral and intravenous administration
RESUMO Mirabegron é um tipo de agonista do receptor adrenérgico beta 3 que demonstra eficácia no tratamento de bexiga hiperativa. Nesta pesquisa, o método UPLC-MS/MS é desenvolvido e validado para o estudo da farmacocinética mirabegron em ratos. Um método de precipitação de proteínas é aplicado para a preparação de amostras com acetonitrilo. 397
Rev. Assoc. Med. Bras.. Publicado em: 2019-02
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2. Associação de ractopamina e vitaminas antioxidantes para suínos em terminação
Objetivou-se neste estudo avaliar a inclusão de ractopamina e sua associação com as vitaminas antioxidantes C e E em dietas de suínos em terminação durante 28 dias antes do abate sobre o desempenho, as características de carcaça e a qualidade da carne. Quarenta e oito suínos da linhagem Agroceres PIC (24 machos castrados e 24 fêmeas) foram distribu
Cienc. Rural. Publicado em: 2015-02
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3. Respostas produtivas e expressão gênica induzidas por períodos de fornecimento de ractopamina para suínos em terminação / Production responses and gene expression induced by ractopamine feeding duration for finishing pigs
O agonista beta-adrenérgico ractopamina (RAC) modifica a composição da carcaça suína por aumentar a massa muscular e reduzir a deposição de gordura. O objetivo neste estudo foi avaliar os efeitos do tempo de fornecimento de RAC sobre o desempenho, concentração de ureia plasmática (CUP), características de carcaça e expressão gênica dos receptor
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2012
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4. Papel dos canais K+ATP na resposta eletrofisiológica ao FSH e ao isoproterenol em células de Sertoli
Follicle-stimulating hormone (FSH) produces a dual effect on the membrane potential of Sertoli cells, with an initial rapid phase, which comprises a hyperpolarization for a period of seconds and a depolarization phase, wich occurs more slowly, within minutes. The depolarization phase involves calcium entry stimulated by FSH. Isoproterenol, an agonist of ¿-a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011
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5. Ractopamina para suínos : efeitos no desempenho, qualidade de carcaça e carne, parâmetros sanguíneos e comportamento
An experiment was conducted where was evaluated the different levels of a beta adrenergic agonist (ractopamine) in feed for finishing pigs during 21 days before the slaughter. Were used 36 pigs (Landrace X Large White), 18 barrows and 18 females with initial weight of 87 kg, continuing two animals of same gender per pen totaling 18 pens, where received water
Publicado em: 2008
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6. Modelo experimental e intrumentação para estudo da função do reticulo sarcoplasmatico no transporte de Ca 2+ no coração / Experimental model and instrumentation for the study of sarcoplasmic reticulum Ca 2+ transport in the heart
The goal of this work was to develop an instrument for simultaneous measurement of cell shortening and cytosolic Ca2+ concentration ([Ca2+]i), by using the fluorescent Ca2+ indicator fluo-3. The instrument was applied to study the uptake of cytosolic Ca2+ by the sarcoplasmic reticulum (RS) Ca2+- ATPase (SERCA, the main transporter responsible for cell relaxa
Publicado em: 2007
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7. Metabolic markers following beta-adrenoceptor agonist infusion in footshock-stressed rats
Stress hormones can alter metabolic functions in adipose tissue and liver, as well as the sensitivity of rat white adipocytes and rat atrial responses to ß-adrenergic agonists. In this study, we examined the effects of three daily footshock stress sessions on the plasma corticosterone, glucose, glycerol and triacylglycerol levels of fed, conscious male rats
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-09
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8. Estudo do efeito da dobutamina (Dobutrex) R e da radiação laser sobre a ação hidrosmotica da vasopressina em bexiga de sapo "in vitro"
In the present work the effects of several pharmacological agents in special Dobutamine and a physical agent-Laser radiation - on the events that follow the interaction of Vasopressin with membrane receptors related to syn¬thesis and inactivation of cyclic-AMP in the toad bladder, are described and characterized. Water flow across the membrane was measured
Publicado em: 1991
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9. Reduced beta-adrenergic receptor activation decreases G-protein expression and beta-adrenergic receptor kinase activity in porcine heart.
To determine whether beta-adrenergic receptor agonist activation influences guanosine 5'-triphosphate-binding protein (G-protein) expression and beta-adrenergic receptor kinase activity in the heart, we examined the effects of chronic beta 1-adrenergic receptor antagonist treatment (bisoprolol, 0.2 mg/kg per d i.v., 35 d) on components of the myocardial beta
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10. Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.
beta-Adrenergic receptor kinase (beta-AR kinase) is a cytosolic enzyme that phosphorylates the beta-adrenergic receptor only when it is occupied by an agonist [Benovic, J. Strasser, R. H., Caron, M. G. & Lefkowitz, R. J. (1986) Proc. Natl. Acad. Sci. USA 83, 2797-2801.] It may be crucially involved in the processes that lead to homologous or agonist-specific
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11. Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.
Binding of the beta-adrenergic agonist [3H]hydroxybenzylisoproterenol to the beta-adrenergic receptor of rat reticulocyte membranes results in the coupling of the receptor to the guanine nucleotide regulatory protein associated with the adenylate cyclase system. This regulatory component, referred to as the G-protein, was identified by its specific [32P]-ADP
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12. Hypothalamic Alpha- and Beta-Adrenergic Systems Regulate Both Thirst and Hunger in the Rat
Adrenergic and adrenolytic drugs were injected directly into the hypothalamus of the rat brain through permanently implanted cannulas and were found to have reliable effects on water consumption in water-satiated and water-deprived subjects. The beta-adrenergic agonist stimulated thirst, and the beta-adrenergic blocker suppressed thirst. Conversely, the alph