Bacterial Lipopolysaccharide
Mostrando 13-24 de 1042 artigos, teses e dissertações.
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13. Human monocytes tolerant to LPS retain the ability to phagocytose bacteria and generate reactive oxygen species
Tolerance to lipopolysaccharide (LPS) occurs when animals or cells exposed to LPS become hyporesponsive to a subsequent challenge with LPS. This mechanism is believed to be involved in the down-regulation of cellular responses observed in septic patients. The aim of this investigation was to evaluate LPS-induced monocyte tolerance of healthy volunteers using
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-09
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14. Interleukin-1 beta and interleukin-8 in healthy and inflamed dental pulps
After aggression to the dental pulp, some cells produce cytokines in order to start and control the inflammatory process. Among these cytokines, interleukin-1 beta (IL-1β) and interleukin-8 (IL-8) emerge as important ones. OBJECTIVE: The purpose of this study was to analyze the location, distribution and concentration of these cytokines in healthy and infla
Journal of Applied Oral Science. Publicado em: 2009-10
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15. Evaluation of adjuvants in new triple bacterial vaccine formulation. / Avaliação de adjuvantes em novas formulações de vacina tríplice bacteriana.
The whole cell pertussis vaccines present some reactogenicity and the acellular, less reactogenic, have prohibitive use due to its high cost. Instituto Butantan developed a less reactogenic whole cell pertussis vaccine (Plow), with low lipopolysaccharide content and an acellular vaccine (Pa), by simple and economic methodology. These preparations, combined t
Publicado em: 2009
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16. Passive acquisition of maternal IgG antibodies reactive to lipopolysaccharide from enterobacteria incident in neonatal infections by preterm and term neonates. / Aquisição passiva de anticorpos IgG maternos reativos com os lipopolissacarídeos de enterobactérias incidentes em infecções neonatais por recém-nascidos pré-termos e a termo.
As espécies Klebsiella pneumoniae, Escherichia coli e Pseudomonas aeruginosa são responsáveis por infecções neonatais hospitalares. Lipopolissacarídeo (LPS) é o principal indutor de respostas inflamatórias. Os objetivos foram avaliar a transferência placentária de IgG reativa ao LPS de K. pneumoniae, E. coli O111, O26 e O6 e P. aeruginosa empregand
Publicado em: 2009
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17. Insights into the regulation of TNF-a production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition
OBJECTIVE: The objective of this study was to determine the effect of nonspecific phosphodiesterase inhibition on transcription factor activation and tumor necrosis factor-alpha (TNF-a) production in lipopolysaccharide (LPS)-stimulated human mononuclear cells. INTRODUCTION: The production of TNF-a following LPS stimulation is one of the key steps in bacteria
Clinics. Publicado em: 2008
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18. Papel da flagelina e de lipopolissacarídeos bacterianos na ativação de populações heterogêneas de macrófagos / The role of bacterial flagellin and lipopolysaccharide on the activation of heterogeneous macrophage subpopulations.
Os macrófagos (MO) são populações heterogêneas de células residentes em diversos tecidos, onde iniciam a resposta imune através do reconhecimento de padrões moleculares de patógenos. Para avaliar a modulação funcional dessas populações, MO peritoneais (PM) e alveolares (AM), com perfil M1 e M2, foram ativados in vivo por flagelina (FliCi) e lipo
Publicado em: 2007
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19. Neutrophil transepithelial migration: role of toll-like receptors in mucosal inflammation
The symptomatic phases of many inflammatory diseases are characterized by migration of large numbers of neutrophils (PMN) across a polarized epithelium and accumulation within a lumen. For example, acute PMN influx is common in diseases of the gastrointestinal system (ulcerative colitis, Crohn's disease, bacterial enterocolitis, gastritis), hepatobiliary sys
Memórias do Instituto Oswaldo Cruz. Publicado em: 2005-03
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20. Esvaziamento gastrico de liquidos em ratos com infarto experimental do miocardio
The Gastric Emptying (GE) is the transition of food from the stomach to the upper small intestine, and could be modify by haemodinamics changes as occur in myocardial infarction (MI). Therefore, the object of the present investigation was to study the effect of acute myocardial infarct on rat gastric emptying and the effect of bacterial lipopolysaccharide in
Publicado em: 2004
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21. Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide
We demonstrated that 4 mM butyrate induces apoptosis in murine peritoneal macrophages in a dose- and time-dependent manner as indicated by studies of cell viability, flow cytometric analysis of annexin-V binding, DNA ladder pattern and the determination of hypodiploid DNA content. The activity of caspase-3 was enhanced during macrophage apoptosis induced by
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-02
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22. Fever induction pathways: evidence from responses to systemic or local cytokine formation
The immune and central nervous systems are functionally connected and interacting. The concept that the immune signaling to the brain which induces fever during infection and inflammation is mediated by circulating cytokines has been traditionally accepted. Administration of bacterial lipopolysaccharide (LPS) induces the appearance of a so-termed "cytokine c
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-03
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23. Synergism between muramyl dipeptide and lipopolysaccharide in the inhibition of glycosaminoglycan synthesis in cultured rat costal chondrocytes.
The effect of synthetic muramyl dipeptide on glycosaminoglycan synthesis in cultured rat costal chondrocytes was examined. Muramyl dipeptide alone had no effect on the glycosaminoglycan synthesis of rat chondrocytes, whereas Escherichia coli lipopolysaccharide and interleukin 1 alpha inhibited glycosaminoglycan synthesis in a dose dependent manner. Muramyl d
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24. Bacterial Lipopolysaccharide: Oral Route for Interferon Production in Mice
Bacterial lipopolysaccharide given orally to mice in relatively small amounts produces significant amounts of circulating interferon.