Azathioprine
Mostrando 25-36 de 183 artigos, teses e dissertações.
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25. Análise de custo-efetividade dos inibidores da rapamicina para o tratamento de imunossupressão no transplante renal
Terminal chronic kidney disease can be treated with hemodialysis (HD), peritoneal dialysis (PD) or by means of renal transplantation. Among these three treatment modalities, the transplant is, according to the literature, the modality that offers better quality of life. Adding to this the progress of the immunosuppressants used in post-transplant, the number
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/06/2012
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26. Desenvolvimento de metodologia para monitorização terapêutica da azatioprina por cromatografia líquida de alta eficiência-UV (HPLC-UV) em transplantados renais / Development of a methodology for therapeutic drug monitoring of azathioprine by high performance liquid chromatography-UV (HPLC-UV) in renal transplant recipients
Azathioprine (AZA) is an immunosuppressant used in autoimmune pathologies like lupus erythematosus, Chrons disease, inflammatory bowel disease and against rejection in solid organs transplant. After more than 40 years of use, AZA continues exerting a central role in immunomodulatory regimens, due to the fact that it combines effectiveness, safety and low cos
Publicado em: 2010
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27. Neuromielite óptica: estudo retrospectivo das características clínicas, radiológicas e análise do tratamento dos pacientes acompanhados no Setor de Neuroimunologia, Disciplina de Neurologia, da Universidade Federal de São Paulo Escola Paulista de Medicina / Neuromyelitis optica: retrospective study on clinical, radiological and treatment analysis of patients followed at the Universidade Federal de São Paulo Escola Paulista de Medicina
Introduction: Neuromyelitis optica (NMO) is an inflammatory, autoimmune, demyelinating disease of the central nervous system associated to antibodies targeted at the aquaporin-4. It is characterized by episodes of acute bilateral optic neuritis and myelitis, and presents as a relapsing-remitting disease in 85% of the cases. Objectives: To describe the demogr
Publicado em: 2010
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28. Lymphocyte subpopulations during cytomegalovirus disease in renal transplant recipients
We have determined the number of circulating T, B and natural killer cells in renal transplant recipients in order to detect changes during cytomegalovirus (CMV) infections. Serial blood samples were taken from 61 patients on standard triple immunosuppression therapy (cyclosporin A, azathioprine and prednisone). Using two-color flow cytometry analysis, the a
Publicado em: 2010
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29. Azatioprina no tratamento de pacientes com doença de Crohn córtico-dependente: resultados no longo prazo e fatores preditivos de resposta
A doença de Crohn é uma afecção intestinal inflamatória crônica, multissistêmica e de caráter recorrente. Sua etiopatogênese permanece ainda desconhecida, mas considera-se haver um cenário fisiopatológico caracterizado, principalmente, pela inibição da imunidade inata com exacerbação da imunidade adaptativa, com atividade inflamatória mucosa
Publicado em: 2010
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30. O uso de imunossupressores e alterações menstruais em pacientes lúpicas / O uso de imunossupressores e alterações menstruais em pacientes lúpicas / The use of immunosuppressants and menstrual disorders in patients with lupus / The use of immunosuppressants and menstrual disorders in patients with lupus
BACKGROUND: The Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects mainly women, and studies have shown that the use of immunosuppressants (IS) during SLE treatment may affect ovarian function. OBJECTIVES: This study aimed at the determination of possible associations in various IS therapeutic schemes and disturb in the ovarian function
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/09/2009
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31. TNF-alfa, IL1-beta and IL-8 expressions in ileal mucosa of Crohn s disease patients using mesalazine or azathioprine / Estudo comparativo das expressões de TNF-alfa, IL1-beta e IL-8 na mucosa ileal de portadores da Doença de Crohn em uso de mesalazina ou azatioprina
Crohn s disease is an inflammatory bowel disease that is not currently understood. Much research is being carried out in order to comprehend its mechanisms of lesion and the inflammatory mediators involved in this disease. New advances in molecular biology have opened up new possibilities for further understanding this intricate pathology, yet, some doubts r
Publicado em: 2009
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32. AZATIOPRINA NO TRATAMENTO DE PACIENTES COM COLITE ULCERATIVA CÓRTICO-DEPENDENTE: RESULTADOS E FATORES PREDITIVOS DE RESPOSTA
Ulcerative colitis (UC) is a lifelong, immune-mediated inflammatory condition of the colonic mucosa, which is characterized by a relapsing and remitting course. Corticosteroids remain one of the most effective therapies for inducing remission in patients with moderate-to-severe UC. Nonetheless, corticosteroids are not used in maintenance therapy, mainly beca
Publicado em: 2009
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33. O uso de imunossupressores e alterações menstruais em pacientes lúpicas / O uso de imunossupressores e alterações menstruais em pacientes lúpicas / The use of immunosuppressants and menstrual disorders in patients with lupus / The use of immunosuppressants and menstrual disorders in patients with lupus
BACKGROUND: The Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects mainly women, and studies have shown that the use of immunosuppressants (IS) during SLE treatment may affect ovarian function. OBJECTIVES: This study aimed at the determination of possible associations in various IS therapeutic schemes and disturb in the ovarian function
Publicado em: 2009
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34. 20 anos de hepatite auto-imune no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo / 20-Year follow up of autoimmune hepatitis in Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Autoimmune hepatitis (AIH) is a chronic liver disease in which there is a progressive destruction of the hepatic parenchyma, leading to cirrhosis without treatment. Previous publications reported some regional and racial differences in clinical, laboratorial, histologic features and treatment response of this disease, probably related to genetic backgrounds
Publicado em: 2008
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35. The incidence of cytomegalovirus infection in lung transplant recipients under universal prophylaxis with intravenous ganciclovir
The best strategy for control of cytomegalovirus (CMV) infection in lung transplant patients is still not determined. The aim of this study was to document the incidence of CMV infection in a cohort of lung transplant recipients under universal prophylaxis with intravenous ganciclovir. All patients received immunosuppressive regimens consisting of cyclospori
Brazilian Journal of Infectious Diseases. Publicado em: 2007-04
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36. Exploratory calcineurin inhibitor-free regimens in living-related kidney transplant recipients
Chronic allograft nephropathy is among the major causes of graft loss even in low-risk kidney transplant recipients and correlates with acute nephrotoxic events during the first year post-transplant. Therefore, calcineurin inhibitor-free regimens may improve patient and graft survival among recipients of living-related kidney transplants. To confirm this hyp
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-04