Attention Pharmaceutical
Mostrando 1-12 de 40 artigos, teses e dissertações.
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1. On the Use of a TiO2 Sol-Gel for Horseradish Peroxidase Enzyme Immobilization for Development of an Amperometric Biosensor
The sol-gel technique has drawn considerable attention in the area of biomolecules immobilization by virtue of its intrinsic properties including chemical inertness, thermal stability, and good biocompatibility. The present work reports the development of a bio-sensing methodology which involves the immobilization of horseradish peroxidase enzyme (HRP) on pe
J. Braz. Chem. Soc.. Publicado em: 2021-06
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2. Novo Qualis: rumos e rumores
Pharmaceutical cocrystals are composed of a drug and a coformer and are currently gaining attention due to their possibility of improving drug solubility. Quantitative determination of cocrystals is usually carried out by liquid chromatography method, but an alternative for the same is derivative UV spectrophotometry. Cocrystals of lamotrigine (LAM) were for
Rev. Bras. Hist.. Publicado em: 2020-12
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3. Development of a First-Order Derivative UV Spectrophotometric Method for the Assay and Solubility Evaluation of Lamotrigine and Nicotinamide Cocrystals
Pharmaceutical cocrystals are composed of a drug and a coformer and are currently gaining attention due to their possibility of improving drug solubility. Quantitative determination of cocrystals is usually carried out by liquid chromatography method, but an alternative for the same is derivative UV spectrophotometry. Cocrystals of lamotrigine (LAM) were for
J. Braz. Chem. Soc.. Publicado em: 2020-12
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4. Methodology Development and Validation of Amphotericin B Stability by HPLC-DAD
The high worldwide consumption of antibiotics and their complex impurity profiles has drawn the attention of the scientific community to the development and validation of stability methods for these drugs. Amphotericin B is an antibiotic that is a natural fermentation product of bacterium Streptomyces nodosus, used as a broad-spectrum antifungal agent, and i
J. Braz. Chem. Soc.. Publicado em: 2020-05
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5. INSAF-HAS: a tool to select patients with hypertension for pharmaceutical care
RESUMO Objetivo Desenvolver e realizar a validação de conteúdo de uma ferramenta para seleção de pacientes com hipertensão arterial sistêmica a serem atendidos em serviços de cuidado farmacêutico, com base na identificação daqueles com maior necessidade dessa assistência. Métodos O instrumento foi desenvolvido e avaliado por validação de fac
Einstein (São Paulo). Publicado em: 13/12/2019
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6. Drug therapy problems for patients with tuberculosis and HIV/AIDS at a reference hospital
RESUMO Objetivo: Determinar a frequência de problemas relacionados ao uso de medicamentos no tratamento de pacientes com tuberculose e HIV/AIDS. Métodos: Os dados foram obtidos por estudo transversal realizado entre setembro de 2015 e dezembro de 2016 em hospital referência em doenças infectocontagiosas de Belo Horizonte (MG), Brasil. As variáveis soc
Einstein (São Paulo). Publicado em: 22/08/2019
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7. Characterization and in silico Mutagenic Assessment of a New Betahistine Degradation Impurity
Currently, the pharmaceutical industry devotes great attention to drug degradation products because these compounds can offer risks to patients. A previous degradation study of betahistine (N-α-methyl-2-pyridylethylamine) conducted under different stress conditions detected three main impurities named A, B and C. Degradation products were analyzed by high-r
J. Braz. Chem. Soc.. Publicado em: 04/07/2019
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8. BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells
Abstract Background: The use of animal venoms and their toxins as material sources for biotechnological applications has received much attention from the pharmaceutical industry. L-amino acid oxidases from snake venoms (SV-LAAOs) have demonstrated innumerous biological effects and pharmacological potential against different cancer types. Hepatocellular carc
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/03/2019
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9. Comprensión de la ciencia al servicio y cuidados de la salud y alteración mental
Abstract Caring for mental health and mental disorders, from primary health attention, is a prime right. The objective of this study was to examine the testimonies of health attention services users regarding the assistance attitudes and practices. This was a hermeneutic qualitative study of several cases. Findings: It can be inferred that there exists a rel
Ciênc. saúde coletiva. Publicado em: 2019-01
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10. A CFD STUDY OF DEPOSITION OF PHARMACEUTICAL AEROSOLS UNDER DIFFERENT RESPIRATORY CONDITIONS
Abstract Respiratory diseases have received increasing attention in recent decades. Airway bifurcations are difficult regions to study, and computational fluid dynamics (CFD) offers an alternative way of evaluating the behavior of pharmaceutical aerosols used in the treatment of respiratory disorders. In this work, particle deposition was analyzed using a th
Braz. J. Chem. Eng.. Publicado em: 2016-09
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11. CROMATOGRAFIA POR INTERAÇÕES HIDROFILICAS (HILIC): ESTADO DA ARTE E APLICAÇÕES
Hydrophilic interaction liquid chromatography (HILIC) has been gaining increased attention for its effective separation of highly polar compounds, which include carbohydrates, amino acids, pharmaceutical compounds, proteins, glycoproteins, nucleosides, etc. Polar compounds are usually poorly retained on reverse-phase liquid chromatography (RP-HPLC) columns o
Quím. Nova. Publicado em: 2016-02
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12. Determinação da capacidade antirradicalar de produtos naturais utilizando-se a quimiluminescência do luminol e ensaios fotométricos com radicais estáveis / Determination of natural product antiradical capacity using luminol chemiluminescence and photometric assays with stable radicals
Living organisms are exposed to the oxidative action of reactive oxygen species (ROS), causing a series of degenerative diseases such as cancer, atherosclerosis, diabetes, arthritis and heart disease. Studies have shown that consumption of antioxidant substances in the daily diet can prevent these oxidative processes that cause premature aging of the organis
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/09/2011