Atp Binding Cassette Transporter
Mostrando 1-12 de 265 artigos, teses e dissertações.
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1. Comparative transcriptome profile of the leaf elongation zone of wild barley (Hordeum spontaneum) eibi1 mutant and its isogenic wild type
Abstract The naturally occurring wild barley mutant eibi1/hvabcg31 suffers from severe water loss due to the permeable leaf cuticle. Eibi1/HvABCG31 encodes a full ATP-binding cassette (ABC) transporter, HvABCG31, playing a role in cutin deposition in the elongation zone of growing barley leaves. The eibi1 allele has pleiotropic effects on the appearance of l
Genet. Mol. Biol.. Publicado em: 23/10/2017
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2. A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
Benznidazole (BZ) is one of the two drugs used for Chagas disease treatment. Nevertheless therapeutic failures of BZ have been reported, which were mostly attributed to variable drug susceptibility among Trypanosoma cruzi strains. ATP-binding cassette (ABC) transporters are involved in a variety of translocation processes and some members have been implicate
Mem. Inst. Oswaldo Cruz. Publicado em: 28/04/2015
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3. Evaluation of the role of ATP-binding cassette transporters as a defence mechanism against temephos in populations of Aedes aegypti
The role of ATP-binding cassette (ABC) transporters in the efflux of the insecticide, temephos, was assessed in the larvae of Aedes aegypti. Bioassays were conducted using mosquito populations that were either susceptible or resistant to temephos by exposure to insecticide alone or in combination with sublethal doses of the ABC transporter inhibitor, verapam
Mem. Inst. Oswaldo Cruz. Publicado em: 2014-11
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4. Efeito dos ácidos graxos saturados, poli-insaturados e trans no desenvolvimento de aterosclerose e esteatose hepática em camundongos com ablação gênica do receptor de LDL / Effect of saturated, polyunsaturated and trans fatty acids on the development of atherosclerosis and hepatic steatosis of mice with ablation of the LDL receptor gene
Introduction: The amount and type of dietary fat play important roles on the development of cardiovascular disease (CVD) and on the development of hepatic steatosis. Saturated (SAT) and trans (TRANS) fatty acids are known as pro-atherogenic, while the polyunsaturated (POLY) fats seem to exert an antiatherogenic action. Regarding hepatic steatosis, it is know
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/12/2012
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5. Efeito da ingestão crônica de dieta hiperlipídica no metabolismo de ratas, e sobre a expressão de SR-BI e ABCA1 na placenta, intestino delgado, fígado e rins da prole destes animais = : Effect of high fat diet chronic ingestion on the metabolism of female rats, and on the SR-BI and ABCA1 expression in the placenta, small intestine, liver and kidney of the offspring / Effect of high fat diet chronic ingestion on the metabolism of female rats, and on the SR-BI and ABCA1 expression in the placenta, small intestine, liver and kidney of the offspring
Devido ao maior consumo de alimentos ricos em gordura e um estilo de vida mais sedentário, houve um aumento na incidência de desordens metabólicas relacionadas ao metabolismo lipídico como a resistência à insulina, dislipidemias, e sua associação com doenças cardiovasculares. A alimentação materna desequilibrada, durante a gestação e lactação,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/08/2012
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6. Estudos estruturais e funcionais das enzimas SsuD e SsuE do sistema de transporte do tipo ABC de alcano sulfonatos e da proteína ligadora periplasmática PbP da bactéria Xanthomonas axonopodis pv.citri / Structural and funcional studies of the enzymes SsuD and SsuE from the alkanesulphonate ABC transporter and the periplasmic binding protein (PbP) from Xanthomonas axopodis pv.citri
A captação de sulfato em Escherichia coli é dependente do transportador do tipo ABC (do inglês, ATP Binding Cassete), SbpCysAWD, pertencente a um regulon que envolve 26 genes. Na ausência de sulfato, a bactéria induz a expressão de dois outros transportadores ABC, o de proteínas do sistema de transporte de alcanosulfonatos (SsuABCDE) e de sulfonatos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/01/2011
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7. Inhibition of Saccharomyces cerevisiae Pdr5p by a natural compound extracted from Brazilian Red Propolis
Multidrug resistance of cancer cells and pathogenic microorganisms leading to the treatment failure of some forms of cancer or life-threatening bacterial or fungal infections is often caused by the overexpression of multidrug efflux pumps belonging to the ATP-binding cassette transporters superfamily. The multidrug resistance of fungal cells often involves t
Revista Brasileira de Farmacognosia. Publicado em: 12/08/2011
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8. Host genetic and epigenetic factors in toxoplasmosis
Analysing human genetic variation provides a powerful tool in understanding risk factors for disease. Toxoplasma gondii acquired by the mother can be transmitted to the fetus. Infants with the most severe clinical signs in brain and eye are those infected early in pregnancy when fetal immunity is least well developed. Genetic analysis could provide unique in
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-03
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9. Identification of citrus expressed sequence tags (ESTs) encoding pleiotropic drug resistance (PDR)-like proteins
Pleiotropic drug resistance (PDR) proteins, a subfamily of the ATP-binding cassette (ABC) transporters, have been recently shown to play a role in plant defense against biotic and abiotic stresses. However, nothing is known about their expression in citrus. To investigate the occurrence of PDR homologues in citrus species, we have surveyed EST sequences from
Genetics and Molecular Biology. Publicado em: 2007
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10. ABCA1 gene expression and polymorphisms on patients under hypolipemic therapy / Estudo da expressão gênica e de polimorfismos do gene ABCA1 em indivíduos sob terapia hipolipemiante
A ATP-binding cassette transporter A1 (ABCA1) é uma proteína transmembrana responsável pelo efluxo celular de colesterol e fosfolipídeos, que é um passo essencial para o transporte reverso do colesterol e para a biogênese da HDL. Polimorfismos do gene ABCA1 foram associados com risco de doença arterial coronariana, variações no perfil lipídico e di
Publicado em: 2007
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11. The MalK protein of the ATP-binding cassette transporter for maltose of Escherichia coli is accessible to protease digestion from the periplasmic side of the membrane.
The ATP-hydrolyzing subunit MalK of the ATP-binding cassette transporter for maltose of Escherichia coli is demonstrated to be accessible to digestion by proteinase K in right-side-out membrane vesicles. This finding suggests a partial transmembrane orientation of the protein.
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12. Trapping the transition state of an ATP-binding cassette transporter: Evidence for a concerted mechanism of maltose transport
High-affinity uptake into bacterial cells is mediated by a large class of periplasmic binding protein-dependent transport systems, members of the ATP-binding cassette superfamily. In the maltose transport system of Escherichia coli, the periplasmic maltose-binding protein binds its substrate maltose with high affinity and, in addition, stimulates the AT
The National Academy of Sciences.