Asthma Pathology
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Dimensões das vias aéreas na asma fatal e na doença pulmonar obstrutiva grave / Airway dimensions in fatal asthma and severe COPD
Background: In some patients with chronic asthma, clinical and physiological similarities with chronic obstructive pulmonary disease may co-exist, such as partial reversibility to bronchodilators despite persistent expiratory airflow obstruction. However, pathologic analyses comparing both diseases in patients of similar age and disease severity are scarce.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/09/2011
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2. Innate immunity in fatal asthma / Imunidade inata na asma fatal
INTRODUÇÃO: A inflamação das vias aéreas na asma envolve respostas imunes inatas. Os receptores do tipo Toll (Toll-like receptors, TLRs) e a citocina linfopoetina do estroma tímico (thymic stromal lymphopoietin, TSLP) estão envolvidos na inflamação brônquica da asma, mas a expressão destas proteínas em vias aéreas grandes e pequenas de asmático
Publicado em: 2010
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3. Evaluation of the ultrastructure and of the movement of cilia in children with chronic and repetition pneumopathies without a defined diagnosis / Avaliação da ultraestrutura e do movimento ciliar em crianças com pneumopatias crônicas e de repetição se diagnóstico definido
INTRODUCTION: Primary ciliary dyskinesia (PCD) is a genetic disorder of the ultrastructure and function of mobile cilia, with consequent impairment of mucociliary clearance, leading to upper and lower airways respiratory infection and infertility. The diagnosis, based on ultrastructure evaluation or genetic scan, is performed according to patient selection a
Publicado em: 2010
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4. Efeitos da nebulizaÃÃo com broncodilatadores carreados pelo heliox associada ao posicionamento corporal em pacientes com crise aguda de asma
Asthma is a respiratory pathology, the treatment of which is primarily pharmacological. Other therapeutic strategies may be used in clinical practice to aid in and/or optimize the treatment of this pathology. Heliox and physiotherapy have been studied with the aim of determining the effects of these resources on the treatment of individuals with asthma. Heli
Publicado em: 2009
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5. Influencia da obesidade no desenvolvimento da asma alergica experimental / Influence of obesity on allergic asthma development
Increases in eosinophil (EO) numbers in the tissues, blood, and bone marrow (BM) are a hallmark of asthma and, in general, elevated numbers correlate with disease severity. Epi-demiological data indicate that obesity increases the prevalence and incidence of allergic asthma. The basis for this relationship is unknown, but might be the result of common eti-ol
Publicado em: 2009
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6. Schistosoma mansoni infection modulates the immune response against allergic and auto-immune diseases
Chronic Schistosoma mansoni infection leads to a type 2-immune response with increased production of interleukin (IL-10). Evidence indicates chronic exposure to S. mansoni down regulates the type 1 immune response and prevents the onset of Th1-mediated diseases such as multiple sclerosis, diabetes mellitus and Cronh's disease. Furthermore, our own studies ha
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-08
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7. Asthma—its Pathology and Treatment
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8. Monoclonal antibodies and other biologic agents in the treatment of asthma
Asthma represents a syndrome of airway inflammatory diseases with complex pathology. The immunologic pathogenesis is being increasingly revealed and provides opportunity for targeted biological intervention. Current experience with immunomodulators as targeted therapy in asthma is described in this literature review. Targeted therapies have included strategi
Landes Bioscience.
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9. Some histological changes in chronic bronchitis and asthma
The differences in two groups of patients (24 with chronic bronchitis and 24 with bronchial asthma) were compared by bronchoscopy and bronchial biopsies. The same investigations were carried out on 24 healthy control subjects. The only bronchoscopic difference between the two groups was hypertonicity of the bronchial wall, which was frequent in the asthmatic
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10. Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
IL-9 is a pleiotropic cytokine with multiple functions on many cell types involved in the pathology of human asthma. The constitutive overexpression of IL-9 in the lungs of transgenic mice resulted in an asthma-like phenotype. To define the contribution of IL-9 to lung inflammation we generated transgenic mice in which lung-specific expression of the IL-9 tr
American Society for Clinical Investigation.
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11. An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy?
The asthma prevalence was increasing over the past two decades worldwide. Allergic asthma, caused by inhaled allergens of different origin or by food, is mediated by inflammatory mechanisms. The action of non-allergic asthma, induced by cold air, humidity, temperature or exercise, is not well understood. Asthma affects up to 15% of the population and is trea
Blackwell Publishing Ltd.
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12. Prevalence of asthma and COPD in general practice in 1992: has it changed since 1977?
BACKGROUND: Asthma and COPD are common diseases of the airways which are mainly diagnosed and treated in general practice. AIM: Various studies have reported an increase in the morbidity of asthma and COPD. There are two possible reasons for such an increase. The first is an apparent increase caused by using different criteria in defining asthma/COPD, and by