Yeasts isolated from patients in University hospital city of Taubate-SP. / Leveduras isoladas de pacientes internados em hospital universitário da cidade de Taubaté - SP.

AUTOR(ES)

Sonia Khouri Crosariol

DATA DE PUBLICAÇÃO

2010

RESUMO

In recent years, there have been a considerable increase of fungal infections in hospitals. Estimates of the incidence of fungal infections do not correspond to reality, due to diagnostic difficulties of these microorganisms. Although fungal infections, especially Candida species, are gaining importance in hospitalized patients, the vast majority of institutions are not yet prepared for the diagnosis of these episodes. The present work aims to perform an epidemiological study, determining the prevalence of these strains isolated from different materials, different sectors in inpatients of a university hospital in the region of Vale do Paraíba-SP. In this study we isolated 55 yeast strains from 558 samples in the period from February to August 2002. The genus Candida occupied the 2nd position (9.85%) for the 10 microorganisms isolated from positive samples with clinical suspicion of nosocomial infection. Samples were positive for yeasts, the most frequent species was C. albicans with 40.0%, followed by C. tropicalis 25.5% C. parapsilosis with 23.6% and 9.1% with C. glabrata and C. norvagensis 1.8%. The medical clinic was the sector that had the greatest number of samples positive for yeast (63.6%), followed by neonatal ICU (20.0%) and adult ICU (16.4%). Among the clinical specimens examined, the secretions (47.3%), in general, presented the largest number of samples positive for yeast, in 2nd place probe tip (29.1%) and blood in 3rd place (12.7%), predominantly C. albicans. Of the 38 patients who presented positive culture for Candida species, 26 cases of colonization were identified (68.4%) and 22 cases were classified as cases of nosocomial infection (57.8%), where 50% of these cases were patients died. The results demonstrate the importance of correct identification of episodes of infection, to characterize the epidemiological profile, thereby aiding in the diagnosis and treatment of these emerging agents.

ASSUNTO(S)

candida spp. candida spp. caracterização de fungos epidemiologia epidemiology infecção hospitalar leveduras nosocomoial infection yeasts yeasts caracterization

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