Variação de peso em usuarias de sistema intra-uterino liberador de levonorgestrel, acetato de medroxiprogesterona de deposito e dispositivo intra-uterino de t-cobre por cinco anos

AUTOR(ES)

Daniela Angerame Yela

DATA DE PUBLICAÇÃO

2004

RESUMO

The objective of the study was to assess the weight variations in Brazilian users of the 20 µg/day levonorgestrel-releasing intrauterine system (LNG-IUS, Mirena®) and to compare them to a cohort of users of the TCu 380A intrauterine device (IUD) and to another cohort of users of the injectable contraceptive, depot-medroxyprogesterone acetate (DMPA) during five years of use. A total of 163 users of the LNG-IUS, who had the device inserted in 1998, were admitted to the study. Each woman was matched by weight (± 1kg) and age (± 1year) at the time of enrollment to a woman using a TCu 380A IUD and to another woman using DMPA. All women were followed up for a maximum of 5 years. Weight was measured yearly during five years and the body mass index (BMI,kg/m2) was calculated. The age of the LNG-IUS users was 27.0 ± 6.7 years (mean ± SD), while the age of the copper IUD users was 28.0 ± 6.6 years and that of DMPA users was 26.9 ± 6.5 years. The weight recorded at the beginning of the study was 62.9 ± 0.8kg, 62.8 ± 0.8kg, and 62.5 ± 0.9kg (Mean ± SD) for users of the LNG-IUS, the copper IUD, and DMPA, respectively. The BMI of women at the beginning of the study was 25.0 (±0.3), 26.4 (±0.3), and 25.5 (±0.4), (Mean ± SD), for users of the LNG-IUS, copper IUD, and DMPA, respectively. Increases in weight of 3.1kg, 4.9kg and 8.2kg were observed in the fifth year among users of the LNG-IUS, copper IUD, and DMPA, respectively (p = 0.009). Increase in BMI was observed among all the groups too (BMI at the end was 26.3 ± 0.7, 28.5 ± 0.8 and 28.7 ± 1.3 for users of the LNG-IUS, copper IUD and DMPA, respectively). Multivariate analysis showed that the time of use of the contraceptive method and the use of DMPA were significantly associated with weight increase. In conclusion, the use of a LNG-IUS resulted in no significant weight increase during the 5 years of use and the difference in weight was of the same magnitude as that of copper IUD users

ASSUNTO(S)

obesidade anticoncepção

Documentos Relacionados

• Variação de peso em usuárias de sistema intra-uterino liberador de levonorgestrel, DIU T-cobre e acetato de medroxiprogesterona no Brasil
• Sistema intra-uterino liberador de levonorgestrel
• Avaliação da massa ossea em usuarias do sistema intra-uterino liberador de levonorgestrel (SIU-LNG)
• Aplicação de dispositivo intra-uterino liberador de levonorgestrel, previamente a ciclos de fertilização in vitro, nas portadoras de adenomiose
• Correlação entre histologia endometrial e padrão de sangramento em usuarias do sistema intra-uterino liberador de levonorgestrel