UTILIZATION OF PYRIMIDINES AND PYRIMIDINE DEOXYNUCLEOSIDES BY THERMOBACTERIUM ACIDOPHILUM (LACTOBACILLUS ACIDOPHILUS)
AUTOR(ES)
Løvtrup, Søren
RESUMO
Løvtrup, Søren (University of Göteborg, Sweden) and David Shugar. Utilization of pyrimidines and pyrimidine deoxynucleosides by Thermobacterium acidophilum (Lactobacillus acid-ophilus). J. Bacteriol. 82:623–631. 1961.—The utilization of pyrimidine deoxynucleosides was investigated by means of deoxyribosides of unnatural pyrimidines, especially by halogen-substituted uracil derivatives. All investigated deoxyribosides could be used, except that of N-methylthymidine. It was concluded that this substance cannot be a substrate for the enzyme trans-N-deoxyribosylase, which has been shown to be active in the utilization of deoxyribosides in this microorganism. With uracil as the only pyrimidine source, the halogen-substituted deoxyuridines had a certain inhibitory effect on growth.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=279228Documentos Relacionados
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