Utilization of Indole Analogs by Carrot and Tobacco Cell Tryptophan Synthase in Vivo and in Vitro1
AUTOR(ES)
Widholm, Jack M.
RESUMO
Twenty-three indole analogs were used to inhibit the growth of carrot and tobacco suspension cultures. The addition of tryptophan or indole partially reversed the inhibition of both cell lines only for 4-fluoroindole, 5-fluoroindole, and 6-fluoroindole. Inhibition of tobacco cell growth by 5-aminoindole, 5-methoxyindole, 6-methoxyindole, or 7-methoxyindole was also partially reversed. Previously selected carrot and tobacco lines, which have high free tryptophan levels, grew in the presence of the analogs for which reversal was noted in all cases except 5-aminoindole and also in some other cases. Growth inhibition caused by all 10 tryptophan analogs studied was partially reversible by tryptophan or indole and the high tryptophan lines were also able to grow in the presence of concentrations inhibitory to the wild type lines.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=425842Documentos Relacionados
- Dissimilation of Tryptophan and Related Indolic Compounds by Ruminal Microorganisms In Vitro1
- A COMPARISON OF EIGHT ANTIBIOTIC AGENTS, IN VIVO AND IN VITRO1
- The Dark Reactions of Rye Phytochrome in Vivo and in Vitro1
- Effect of Tryptophan Analogs on Derepression of the Escherichia coli Tryptophan Operon by Indole-3-Propionic Acid
- CHLORAMPHENICOL-FASTNESS: DEVELOPMENT IN VIVO AND EXPERIMENTAL PRODUCTION IN VITRO1
