Use of Single Urine Samples for the Assessment of Lead Absorption

AUTOR(ES)

Molyneux, M. K. B.

RESUMO

The variation of urinary lead concentration (μg. Pb/litre) of short-period samples has been studied in a group of men exposed to inorganic lead dust. The urinary specific gravity was used to correct for the variation in urinary volume, but the residual variation was still too great to assess the mean lead concentration. The effect of creatinine correction was studied as an alternative, but there is no statistical difference between either method of correction. It is shown that the variation of lead concentration is related to the time of day. The highest concentration occurs at approximately 4.00 p.m. in day workers.

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