Unusual presentation of a disseminated oral HPV infection after combined antiretroviral therapy initiation

AUTOR(ES)

Vale, Daniela Assis do

FONTE

Rev. Inst. Med. trop. S. Paulo

DATA DE PUBLICAÇÃO

10/10/2019

RESUMO

ABSTRACT HPV clinical manifestations have their characteristics modified by the use of combined antiretroviral therapy (cART), although its incidence is unaffected by cART. We report an unusual presentation of oral HPV infection and discuss an effective treatment for disseminated HPV lesions. A 52-year-old male of Asian-origin, HIV-seropositive, presented with extensive nodular lesions throughout the oral mucosa extending to the oropharyngeal region. Biopsy followed by histopathological examination and HPV genotyping were performed. The treatment was initiated with topical application of podophyllin and trichloroacetic acid. HPV lesions in oral mucosa are generally easy to handle. Extensive lesions can make it difficult to choose an effective treatment that meets the patient’s particularities and medication availability.

Documentos Relacionados

• Oral HPV infection in a bone marrow transplantation patient: a case report with atypical clinical presentation and unexpected outcome
• Immune therapy of a persistent and disseminated viral infection.
• Disseminated herpes simplex virus infection with misleading clinical presentation.
• Antiretroviral combination therapy and HIV infection
• Adverse effects of antiretroviral therapy for HIV infection