UK clinicians' knowledge of and attitudes to the prenatal diagnosis of single gene disorders.

AUTOR(ES)

Firth, H V

RESUMO

Postal questionnaires were sent to 308 clinicians in the UK (general practitioners, obstetricians, clinical geneticists, neurologists, paediatricians, and paediatric neurologists) to assess their knowledge of, and attitudes to, the prenatal diagnosis of three common single gene disorders, Huntington's disease (HD), cystic fibrosis (CF), and Duchenne muscular dystrophy (DMD). Replies received numbered 213, a response rate of 69%. Overall, 95% of responding clinicians thought that offering prenatal diagnosis for the three test conditions was often or always appropriate. There was a correlation between the clinicians' estimates of life expectancy and their willingness to offer prenatal diagnosis (p less than 0.01). Among the non-geneticists questioned, fewer than 50% of general practitioners answered correctly regarding the availability of prenatal tests.

Documentos Relacionados

• Prenatal diagnosis of genetic disorders.
• Prenatal diagnosis of the common haemoglobin disorders.
• Attitudes and behaviors towards clinical guidelines: the clinicians' perspective.
• Adult polycystic kidney disease: knowledge, experience, and attitudes to prenatal diagnosis.
• Evidence based practice: clinicians' use and attitudes to near patient testing in hospitals.