Type 2 diabetes mellitus-related environmental factors and the gut microbiota: emerging evidence and challenges
AUTOR(ES)
Liu, Yanfen
FONTE
Clinics
DATA DE PUBLICAÇÃO
10/01/2020
RESUMO
The gut microbiota is a group of over 38 trillion bacterial cells in the human microbiota that plays an important role in the regulation of human metabolism through its symbiotic relationship with the host. Changes in the gut microbial ecosystem are associated with increased susceptibility to metabolic disease in humans. However, the composition of the gut microbiota in those with type 2 diabetes mellitus and in the pathogenesis of metabolic diseases is not well understood. This article reviews the relationship between environmental factors and the gut microbiota in individuals with type 2 diabetes mellitus. Finally, we discuss the goal of treating type 2 diabetes mellitus by modifying the gut microbiota and the challenges that remain in this area.
Documentos Relacionados
- Role of nitric oxide in insulin-dependent diabetes mellitus-related vascular complications.
- Translational research into gut microbiota: new horizons on obesity treatment: updated 2014
- Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes
- Environmental Influences on Development of Type 2 Diabetes and Obesity: Challenges in Personalizing Prevention and Management
- Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus