Truncated forms of the polyomavirus middle T antigen can substitute for the small T antigen in lytic infection.
AUTOR(ES)
Templeton, D
RESUMO
Cloned polyomavirus genomes encoding the small T antigen or truncated forms of the middle T antigen facilitated the growth of genomes encoding only the large T antigen in mouse 3T6 cells. We conclude that an N-terminal domain of the middle T antigen, in the appropriate cellular location, can substitute for the small T antigen during lytic infection.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=252738Documentos Relacionados
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