Tropical biodiversity: has it been a potential source of secondary metabolites useful for medicinal chemistry?

AUTOR(ES)

Valli, Marilia, Pivatto, Marcos, Danuello, Amanda, Castro-Gamboa, Ian, Silva, Dulce Helena Siqueira, Cavalheiro, Alberto José, Araújo, Ângela Regina, Furlan, Maysa, Lopes, Márcia Nasser, Bolzani, Vanderlan da Silva

FONTE

Quím. Nova

DATA DE PUBLICAÇÃO

2012

RESUMO

The use of natural products has definitely been the most successful strategy in the discovery of novel medicines. Secondary metabolites from terrestrial and marine organisms have found considerable use in the treatment of numerous diseases and have been considered lead molecules both in their natural form and as templates for medicinal chemistry. This paper seeks to show the great value of secondary metabolites and emphasize the rich chemical diversity of Brazilian biodiversity. This natural chemical library remains understudied, but can be a useful source of new secondary metabolites with potential application as templates for drug discovery.

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