Transformation of Agrobacterium tumefaciens into a Non-oncogenic Species by an Escherichia coli RNA

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RESUMO

Transforming RNA excreted by showdomycin-resistant Escherichia coli induces a persistent, heritable, and spectacular change in Agrobacterium tumefaciens B6, a bacterium that carries the oncogenic principle for tumor induction in plants. Transformants possessing new physiological and biochemical properties have completely or partially lost the capacity for tumor induction. They synthetize new ribosomes whose components are profoundly modified. On the basis of biological and biochemical characteristics, one is inclined to consider the completely transformed Agrobacterium tumefaciens as a “new species”.

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