“TRANSCRIPTIONAL MAPPING,” I. INTRODUCTION TO THE METHOD AND THE USE OF ACTINOMYCIN D AS A TRANSCRIPTIONAL MAPPING AGENT

AUTOR(ES)

Bleyman, Michael

RESUMO

The transcription process can in theory be used for genetic mapping on the “intraoperonal” level. We have shown that such an approach, utilizing actinomycin D to create blocks to the travel of the transcription enzyme, is indeed feasible, and the effects of actinomycin D on the synthesis of general pulse-labeled RNA are reported herein.

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