Total synthesis of 1-hydroxydehydroherbarin and ascomycones A, B, naphthoquinone antibiotics

AUTOR(ES)

Dong, Wen-Kai, Huang, Xiong, Xu, Dong-Cheng, Li, Xin-Sheng, Xie, Jian-Wu

FONTE

Journal of the Brazilian Chemical Society

DATA DE PUBLICAÇÃO

2012-02

RESUMO

A primeira síntese total de 1-hidróxi-desidroherbarina e ascomyconas A e B é relatada. As ascomyconas A e B biologicamente interessantes foram obtidas com rendimento total de 18% a partir de 3-cloro-2,5-dimetoxibenzaldeído como bloco de construção.

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