Topically administered immunoglobulin reduces pulmonary respiratory syncytial virus shedding in owl monkeys.

AUTOR(ES)

Hemming, V G

RESUMO

A human intravenous immunoglobulin preparation containing neutralizing antibodies to respiratory syncytial virus (RSV) was utilized for intratracheal and topical treatment of laboratory-induced RSV infections in owl monkeys (Aotus trivirgatus). Topically administered antibodies induced significant reductions in RSV shedding in the lower respiratory tract.

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