Topical action of Buriti oil (Mauritia flexuosa L.) in myositis induced in rats
AUTOR(ES)
Barbosa, Marília Ursulino, Silva, Marcello de Alencar, Barros, Esmeralda Maria Lustosa, Barbosa, Margarida Ursulino, Sousa, Rayssilane Cardoso de, Lopes, Mateus Aguiar da Costa, Coelho, Nayana Pinheiro Machado de Freitas
FONTE
Acta Cir. Bras.
DATA DE PUBLICAÇÃO
2017-11
RESUMO
Abstract Purpose: To analyze the topical effects of Buriti oil (Mauritia flexuosa L.) in induced myositis in rats. Methods: Thirty six male rats divided into three groups: Control group (C), induced myositis group (MI) and induced myositis group reated with Mauritia flexuosa L. (MT). After inducing myositis with 1% acetic acid, was topically applied 0.5 ml of Mauritia flexuosa L.extract on the posterior region of the right gastrocnemius muscle in animals belonging to group MT, for 7 and 14 days. Results: The neutrophil number there was statistically significant difference, after 7 and 14 days, between groups C and MI (p <0.001) (p<0.01). The group MT there was a significant difference in relation to MI group in both experimental times with (p<0.001). The number of fibroblasts in the 14 days showed that when comparing the groups M and MT the differences were also significant (p<0.001). As for the DLL, in 7 days, there was a significant difference between group C and MI group (p <0.001). When considering the MT group, there was a significant difference in relation to the MI group (p <0.001). Conclusion: The extract of Mauritia flexuosa L. leaves lessened acute and chronic inflammation, increased fibroblast proliferation and reduced macroscopically edema.
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