The role of resistive physical training during the hospitalization in clinical, functional and quality of life improvement in patients with chronic obstructive pulmonary disease / O papel do treinamento físico resistido durante o periodo de hospitalização na melhora clínica, funcional e da qualidade de vida em pacientes com doença pulmonar obstrutiva crônica

AUTOR(ES)
FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

30/01/2012

RESUMO

BACKGROUND: Exacerbations of chronic obstructive pulmonary disease (COPD) profoundly affects the peripheral muscle strength and functional capacity of patients, however, interventions to prevent these losses and systemic function are poorly understood. OBJECTIVE: Evaluate the effects of resistance training on peripheral muscle strength, functional capacity and quality of life in COPD patients during hospitalization. In addition, evaluate the response of this intervention on systemic inflammation and physical activity of daily living. METHODS: Twenty-nine patients hospitalized in the ward of a university hospital for exacerbation of COPD were randomized into two groups: control (CG) and training (GT). They were evaluated at day 2 after admission, hospital discharge and after 30 days. These assessments were verified to peripheral muscle strength of upper and lower limbs, the distance walked in 6 minutes, systemic inflammation (TNF-, CRP, IL1, IL-12p70, IL-6, IL-8 and IL10), health-related quality of life and physical activity of daily living. RESULTS: Our results show that during hospitalization all patients, regardless of group, remained most of the time (87%) in the lying or sitting position. The CG patients showed a reduction in muscle strength of lower limbs (p <0.05) but no change in distance walked in 6 minutes (p>0.05) during hospitalization. TG patients demonstrated improvement in muscle strength of lower limbs and distance walked in 6 minutes (p <0.05) that remained until 30 days after hospital discharge. Differently from GC, the GT patients showed an improvement in the domain impact on health-related quality of life after discharge. There was no difference between groups in systemic inflammatory markers analyzed during hospitalization and after 30 days. In addition, several patients in both groups remained physically inactive (70%) at home. CONCLUSION: Our results suggest that resistance training during hospitalization improves peripheral muscle strength and functional capacity. However, without altering systemic inflammation and physical activity of daily living

ASSUNTO(S)

hospitalization quality of life systemic inflammation capacidade funcional chronic obstructive pulmonary disease doença pulmonar obstrutiva crônica força muscular functional capacity hospitalização inflamação sistêmica muscle strength qualidade de vida

ACESSO AO ARTIGO

Documentos Relacionados